Khoury S A, Massad D F
Department of Community Medicine, University of Jordan, Amman, Jordan.
Saudi Med J. 2000 Feb;21(2):150-4.
Consanguinity is a wide spread practice in Jordan. The objective of this study is to explore the health effects of consanguinity, in particular fertility, reproductive wastage, infant mortality and congenital malformations.
A stratified 2 stage cluster sample of 1867 married couples, representative of all population groups and all geographic locations of Jordan were randomly selected. A questionnaire was specially designed to explore each of the objectives set for the study and was field tested. A group of field workers were thoroughly trained on the implementation of this instrument. All 1867 couples were interviewed by these field workers and completed questionnaires were reviewed before data entry. Data analysis was carried out using SPSSX statistical package. Significance tests were performed wherever appropriate.
The study showed that fertility, as measured by the number of pregnancies, taking into consideration marriage duration, was not affected by consanguinity. Twin pregnancies and abortions did not show any significant difference between consanguineous and non-consanguineous marriages. Consanguineous marriages showed significantly higher rates of still births and infant mortality in general. Within the consanguineous group, female infant mortality rates were significantly higher than those of males. Congenital malformations as reported by mothers of consanguineous marriages were significantly higher than those reported by mothers of non-consanguineous marriages.
This study showed that consanguinity has a detrimental effect on many aspects of reproductive health.
近亲结婚在约旦是一种普遍现象。本研究的目的是探讨近亲结婚对健康的影响,尤其是生育能力、生殖损耗、婴儿死亡率和先天性畸形。
从约旦所有人口群体和所有地理位置中随机抽取1867对已婚夫妇作为分层两阶段整群样本。专门设计了一份问卷来探讨该研究所设定的每个目标,并进行了实地测试。一组实地工作人员接受了关于该问卷实施的全面培训。所有1867对夫妇均由这些实地工作人员进行访谈,在数据录入前对填写完整的问卷进行了审核。使用SPSSX统计软件包进行数据分析。在适当情况下进行显著性检验。
研究表明,考虑到婚姻持续时间,以怀孕次数衡量的生育能力不受近亲结婚的影响。双胞胎怀孕和流产在近亲结婚和非近亲结婚之间没有显示出任何显著差异。近亲结婚总体上死产和婴儿死亡率显著更高。在近亲结婚组中,女婴死亡率显著高于男婴。近亲结婚母亲报告的先天性畸形显著高于非近亲结婚母亲报告的。
本研究表明,近亲结婚对生殖健康的许多方面有不利影响。