Pubertal development in Caracas upper-middle-class boys and girls in a longitudinal context.

Changes between pubertal stages (PS) are best analyzed in a longitudinal context. A sample of 67 boys and 48 girls from the Caracas Longitudinal Study who presented data for the full range of pubertal development: genitalia (G2-G5), breast (B2-B5), pubic hair (PH2-PH5), axillary hair (AH2-AH3), and age at menarche (AM) during follow-up, were assessed at clinical examination. Medians and standard errors for ages at each stage were estimated with the logit method. For length of intervals between stages of genitalia, breast, pubic hair and axillary hair, intervals B2-M and PH2-M, survival analysis was used according to life tables and Cox regression analysis. In boys, G2 occurred at 11.61 years; in girls, B2 occurred at 10.35 years and AM at 12.55 years of age. In both sexes, length of the intervals PS 2-3 and 3-4 were approximately 1 year, while PS 4-5 was 1.5 years. Duration of puberty reached 3.7 years in boys (G2-G5) and 3.3 years in girls (B2-B5); corresponding intervals for PH2-PH5 were 3.1 and 3.0 years in boys and girls, respectively. B2-AM was 1.8 years (with a range of 0.3-3.6 years) and PH2-AM was 1.5 years (with a range 0.3-3.5 years). These results are useful for screening and monitoring: identifying abnormal pubertal patterns in subjects who are advanced or delayed with respect to their peers, together with other pubertal events such as age at peak height and weight velocity and skeletal age. Am. J. Hum. Biol. 12:88-96, 2000. Copyright 2000 Wiley-Liss, Inc.