一种来自抱茎苦荬菜的新型三萜皂苷及其细胞毒性活性。
A new triterpenoidal saponin from Ixeris sonchifolia and its cytotoxic activity.
作者信息
Feng X Z, Dong M, Xu S X
机构信息
Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Shenyang, P.R. China.
出版信息
Pharmazie. 2001 Aug;56(8):663-4.
PMID:11534348
Abstract
A new triterpenoidal saponin, echinocystic acid 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranoside (1), was isolated from Ixeris sonchifolia. Its structure was elucidated on the basis of full spectral data analysis and chemical methods. The cytotoxic activity of compound 1 was evaluated using the tumor cell lines of A375, Hela, and L929 in vitro.
摘要
从苣荬菜中分离得到一种新的三萜皂苷，即刺囊酸3 - O - β - D - 吡喃葡萄糖基 - (1→3) - α - L - 吡喃阿拉伯糖苷（1）。通过全面的光谱数据分析和化学方法阐明了其结构。在体外使用A375、Hela和L929肿瘤细胞系评估了化合物1的细胞毒性活性。
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