Cheon S H, Park J S, Lee J Y, Lee Y N, Yi H, Chung B H, Choi B G, Cho W J, Choi S U, Lee C O
College of Pharmacy, Chonnam National University, Kwangju, Korea.
Arch Pharm Res. 2001 Aug;24(4):276-80. doi: 10.1007/BF02975091.
Substituted isoquinolin-1-ones (1) were synthesized to test their in vitro anticancer activity. 3-Biphenyl-N-methylisoquinolin-1-one (7) showed the most potent anticancer activity against five different human cancer cell lines.
合成了取代异喹啉-1-酮(1)以测试其体外抗癌活性。3-联苯基-N-甲基异喹啉-1-酮(7)对五种不同的人类癌细胞系显示出最有效的抗癌活性。