Hedges A S, Van Atta L, Thomas J B
Physiol Behav. 1975 Jan;14(1):25-30. doi: 10.1016/0031-9384(75)90136-5.
Normal rats were given 1000 training trials in a discriminated lever-press avoidance task. Those animals which exhibited consistent escape behavior but minimal avoidance responding were subjected to either septal lesions or control operations. One week later they were retested in the avoidance apparatus for an additional 1000 trials. Rats with large septal lesions exhibited an immediate increase in avoidance performance relative to the control rats. This increase occurred without a concomitant increase in number of lever-press responses. The performance of 3 out of 4 rats with smaller more dorsal septal lesions was unaffected by the surgery.
正常大鼠在一个有辨别力的杠杆按压回避任务中接受了1000次训练试验。那些表现出持续逃避行为但回避反应极少的动物接受了隔区损伤或对照手术。一周后，它们在回避装置中再次接受1000次试验的重新测试。与对照大鼠相比，有大面积隔区损伤的大鼠回避表现立即增加。这种增加并没有伴随着杠杆按压反应次数的相应增加。4只背侧隔区损伤较小的大鼠中有3只的表现不受手术影响。
