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伴有外侧隔损伤大鼠的自由操作回避行为:电击强度的影响。

Free-operant avoidance behavior in rats with lateral septal lesions: Effect of shock intensity.

作者信息

Sagvolden T

出版信息

Brain Res. 1976 Jul 16;110(3):559-74. doi: 10.1016/0006-8993(76)90866-0.

DOI:10.1016/0006-8993(76)90866-0
PMID:985709
Abstract

The purpose of experiment 1 was to examine the relationship between shock intensity and normal rats' free-operant (Sidman) avoidance performance on a 3-component, multiple schedule. The results showed an inverted U-shaped relation between response rate and shock intensity, but no consistent relation between shock rate and shock intensity was found. Experiment 2 showed that lateral sptal lesions produced a bidirectional change in reactivity to electric shock. An increased reactivity was observed in the initial sessions starting on the 11th day after the surgery, while a reduced reactivity was observed in the final sessions when stable performance had been reacquired. These changes were not a function of the waning of general hyperreactivity with post-operative recovery: the septal lesions in this study did not produce any "sham rage". From 40 to 80% of the variance in response rates was accounted for by this bidirectional change in the reactivity to shock.

摘要

实验1的目的是研究电击强度与正常大鼠在三分量多重强化程序下的自由操作(西德曼)回避行为之间的关系。结果表明,反应率与电击强度呈倒U形关系,但未发现电击频率与电击强度之间存在一致关系。实验2表明,外侧隔区损伤对电击反应性产生双向变化。术后第11天开始的初始阶段观察到反应性增强,而在重新获得稳定表现的最后阶段观察到反应性降低。这些变化并非术后恢复过程中一般过度反应性减弱的结果:本研究中的隔区损伤未产生任何“假怒”现象。电击反应性的这种双向变化解释了40%至80%的反应率方差。

相似文献

1
Free-operant avoidance behavior in rats with lateral septal lesions: Effect of shock intensity.伴有外侧隔损伤大鼠的自由操作回避行为:电击强度的影响。
Brain Res. 1976 Jul 16;110(3):559-74. doi: 10.1016/0006-8993(76)90866-0.
2
Behavior of rats with septal lesions during low levels of water deprivation.
Behav Neural Biol. 1979 Aug;26(4):431-41. doi: 10.1016/s0163-1047(79)91446-8.
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Discrimination of response-contingent and response-independent shock by rats: effects of medial and lateral septal lesions and chlordiazepoxide.大鼠对反应性和非反应性电击的辨别:内侧和外侧隔区损伤及氯氮卓的影响
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Effects of anterior, posterior, medial, lateral, and total septal lesions upon fixed ratio performance in the rat.前、后、内侧、外侧及全中隔损伤对大鼠固定比率行为表现的影响。
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Septal lesions facilitate the shift from conditioned escape to conditioned avoidance behavior in the rat.中隔损伤促进大鼠从条件性逃避行为向条件性回避行为的转变。
Physiol Behav. 1975 Jan;14(1):25-30. doi: 10.1016/0031-9384(75)90136-5.
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Developmental analysis of behavioral dysfunction in rats with septal lesions.隔区损伤大鼠行为功能障碍的发育分析
J Comp Physiol Psychol. 1977 Feb;91(1):94-106. doi: 10.1037/h0077309.
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[Septum (review of the morphologic and physiologic literature)].
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Operant responding for water in rats with septal lesions: effect of deprivation level.患有中隔损伤的大鼠对水的操作性反应:剥夺水平的影响。
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