Newlands E S
Medical Oncology Department, Charing Cross Hospital, London, England.
Forum (Genova). 2000 Oct-Dec;10(4):368-80.
Malignant ovarian germ cell tumours are rare but they occur in women with a mean age of 19 years. It is important that these young patients are not subjected to radical surgery. In most of these patients, they can be cured with either surgery alone and careful surveillance with a combination of clinical examination, computer tomography scanning and serial serum tumour markers. Almost all of those with metastatic disease can be cured with cisplatin-based chemotherapy. A relapse is rare and most of these young patients will recover menstruation within two to six months of completing their chemotherapy and provided they have not had radical surgery, most of these patients should be able to complete their families normally.
恶性卵巢生殖细胞肿瘤罕见,但发病于平均年龄19岁的女性。重要的是,这些年轻患者不应接受根治性手术。在大多数此类患者中,仅通过手术及结合临床检查、计算机断层扫描和系列血清肿瘤标志物的仔细监测即可治愈。几乎所有转移性疾病患者都可通过以顺铂为基础的化疗治愈。复发罕见,这些年轻患者中的大多数在完成化疗后的两到六个月内会恢复月经,并且只要他们未接受根治性手术,大多数患者应能够正常组建家庭。