Oligomerization of deoxynucleoside-bisphosphate dimers: template and linkage specificity.
作者信息
Visscher J, van der Woerd R, Bakker C G, Schwartz A W
机构信息
Laboratory for Exobiology, University of Nijmegen, The Netherlands.
出版信息
Orig Life Evol Biosph. 1989;19(1):3-6. doi: 10.1007/BF01808283.
PMID:11536610
Abstract
Evidence is presented that a poly(U) template selectively favors the oligomerization of the activated, 3'-5' pyrophosphate-linked dimer pdAppdAp, in comparison with the 3'-3' and 5'-5' linked dimers. In the absence of poly(U), the 5'-5' linked dimer is the most reactive, and chains are formed which are more than 60 monomer units in length.
摘要
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