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普通人群中脊柱骨质增生的流行病学及其症状和相关死亡率。

The epidemiology of hyperostosis of the spine together with its symptoms and related mortality in a general population.

作者信息

Julkunen H, Heinonen O P, Knekt P, Maatela J

出版信息

Scand J Rheumatol. 1975;4(1):23-7.

PMID:1153976
Abstract

The prevalence rate of hyperostosis, defined as the presence of complete bony bridges linking two vertebrae in at least two separate sites in the dorsal spine, was studied in a sample of some 9 000 persons who were 40 years of age or older and were representative of the general population of Finland. The standardized rates of hyperostosis were 3.8% for men and 2.6% for women. The prevalence rates rose sharply with age, and depending on the age group, the male-female ratio varied between 1.4 and 2.1. The adjusted rate of hyperostosis was higher in East Finland than elsewhere. There was a suggestion of hyperostosis being associated with a higher mortality rate as judged by regional variations and by analysis of matched case-controled pairs. There was no evidence that locomotor symptoms occurred in excess in subjects with hyperostosis; nor was prior traumatic experience more common.

摘要

在约9000名40岁及以上、代表芬兰普通人群的样本中,研究了骨质增生的患病率,骨质增生定义为在脊柱背部至少两个不同部位存在连接两个椎体的完整骨桥。骨质增生的标准化患病率男性为3.8%,女性为2.6%。患病率随年龄急剧上升,根据年龄组不同,男女比例在1.4至2.1之间变化。芬兰东部骨质增生的校正患病率高于其他地区。从地区差异以及配对病例对照分析判断,有迹象表明骨质增生与较高的死亡率相关。没有证据表明骨质增生患者出现运动症状的比例过高;既往创伤经历也并不更常见。

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