Schaefer Raymond Osayamen, Rutsch Niklas, Schnake Klaus J, Aly Mohamed M, Camino-Willhuber Gaston, Holas Martin, Spiegl Ulrich, Muijs Sander, Albers Christoph E, Bigdon Sebastian F
Department of Orthopaedic Surgery, Sonnenhof Spital, University Bern, 3006, Bern, Switzerland.
Department of Orthopaedic Surgery and Traumatology, Inselspital University Hospital Bern, 3010, Bern, Switzerland.
Brain Spine. 2024 Apr 15;4:102811. doi: 10.1016/j.bas.2024.102811. eCollection 2024.
Injuries to the rigid spine have a distinguished position in the broad spectrum of spinal injuries due to altered biomechanical properties. The rigid spine is more prone to fractures. Two ossification bone disorders that are of particular interest are Ankylosing Spondylitis (AS) and Diffuse Idiopathic Skeletal Hyperostosis (DISH). DISH is a non-inflammatory condition that leads to an anterolateral ossification of the spine. AS on the other hand is a chronic inflammatory disease that leads to cortical bone erosions and spinal ossifications. Both diseases gradually induce stiffening of the spine. The prevalence of DISH is age-related and is therefore higher in the older population. Although the prevalence of AS is not age-related the occurrence of spinal ossification is higher with increasing age. This association with age and the aging demographics in industrialized nations illustrate the need for medical professionals to be adequately informed and prepared. The aim of this narrating review is to give an overview on the diagnostic and therapeutic measures of the ankylosed spine. Because of highly unstable fracture configurations, injuries to the rigid spine are highly susceptible to neurological deficits. Diagnosing a fracture of the ankylosed spine on plain radiographs can be challenging. Moreover, since 8% of patients with ankylosing spine disorders (ASD) have multiple non-contagious fractures, a CT scan of the entire spine is highly recommended as the primary diagnostic tool. There are no consensus-based guidelines for the treatment of spinal fractures in ASD. The presence of neurological deficit or unstable fractures are absolute indications for surgical intervention. If conservative therapy is chosen, patients should be monitored closely to ensure that secondary neurologic deterioration does not occur. For the fractures that have to be treated surgically, stabilization of at least three segments above and below the fracture zone is recommended. These fractures mostly are treated via the posterior approach. Patients with AS or DISH share a significant risk for complications after a traumatic spine injury. The most frequent complications for patients with thoracolumbar burst fractures are respiratory failure, pseudoarthrosis, pneumonia, and implant failure.
由于生物力学特性改变,僵硬脊柱损伤在广泛的脊柱损伤中占有显著地位。僵硬脊柱更容易发生骨折。两种特别值得关注的骨化性骨病是强直性脊柱炎(AS)和弥漫性特发性骨肥厚(DISH)。DISH是一种非炎症性疾病,可导致脊柱前外侧骨化。另一方面,AS是一种慢性炎症性疾病,可导致皮质骨侵蚀和脊柱骨化。这两种疾病都会逐渐导致脊柱僵硬。DISH的患病率与年龄相关,因此在老年人群中更高。虽然AS的患病率与年龄无关,但随着年龄的增长,脊柱骨化的发生率更高。这种与年龄的关联以及工业化国家人口老龄化的情况表明,医疗专业人员需要充分了解并做好准备。本叙述性综述的目的是概述强直性脊柱的诊断和治疗措施。由于骨折构型高度不稳定,僵硬脊柱损伤极易导致神经功能缺损。在普通X线片上诊断强直性脊柱骨折可能具有挑战性。此外,由于8%的强直性脊柱疾病(ASD)患者有多处非传染性骨折,强烈建议对整个脊柱进行CT扫描作为主要诊断工具。目前尚无基于共识的ASD脊柱骨折治疗指南。神经功能缺损或不稳定骨折的存在是手术干预的绝对指征。如果选择保守治疗,应密切监测患者,以确保不会发生继发性神经功能恶化。对于必须手术治疗的骨折,建议在骨折区域上方和下方至少固定三个节段。这些骨折大多通过后路进行治疗。AS或DISH患者在脊柱创伤后有发生并发症的重大风险。胸腰椎爆裂骨折患者最常见的并发症是呼吸衰竭、假关节形成、肺炎和内植物失败。