Luehrsen K R, Nicholson D E, Fox G E
Department of Biochemical and Biophysical Sciences, University of Houston University Park, Texas, USA.
Curr Microbiol. 1985;12:69-72. doi: 10.1007/BF01567394.
An RNA of nonribosomal origin was found in the extreme halophilic bacteria. This novel small RNA was found to be a homogeneous species by RNA fingerprinting. Analysis of the ribonuclease T1 oligonucleotides gave no evidence of the presence of posttranscriptional modifications. Comparisons of electrophoretic mobility with other RNAs of known size suggest that this is a 7S RNA containing 325-375 nucleotides. An RNA of similar mobility was found in all major divisions of the archaebacteria. Insufficient sequence information is available to determine whether these RNAs are homologs of any other known small RNA.
在极端嗜盐细菌中发现了一种非核糖体来源的RNA。通过RNA指纹图谱分析发现这种新型小RNA是一种均一的分子种类。核糖核酸酶T1寡核苷酸分析没有发现转录后修饰存在的证据。将其电泳迁移率与其他已知大小的RNA进行比较表明,这是一种含有325 - 375个核苷酸的7S RNA。在古细菌的所有主要分类中都发现了一种具有相似迁移率的RNA。目前可获得的序列信息不足,无法确定这些RNA是否与任何其他已知的小RNA是同源物。