Pannier B M, Cuche J L, Benetos A, Boutouyrie P, Safar M E
INSERM, Hopital Broussais, Paris, France.
Acta Astronaut. 1995 Oct-Dec;36(8-12):433-8. doi: 10.1016/0094-5765(95)00128-x.
In cardio-vascular hemodynamic, the arterial pulsatility, represented by the arterial pulse pressure (PP= systolic blood pressure-diastolic blood pressure), is different from one site to another, in opposite with the mean blood pressure almost identical in the whole body in supine position (or in microgravity). This is due to the arterial tree geometry and regional differences in the distensibility properties of the arterial wall. As the level of blood pressure opposed to the cardiac left ventricle work is the central pressure, on one hand and as the arterial pulsatility at the site of arterial baro-receptors (located on aortic arch and carotid arteries' bifurcation) regulates the sympathetic and vagal control of heart and peripheral resistances on the other hand, to determine the evolution of this central pulse pressure is of major importance in the knowledge of cardio-vascular hemodynamic during hyper or hypogravity as observed during parabolic flights. The aim of this study was to evaluate noninvasively the carotid artery pulsatility and mechanic properties during parabolic flights.
在心血管血液动力学中，由动脉脉压（PP = 收缩压 - 舒张压）表示的动脉搏动性在不同部位有所不同，这与仰卧位（或微重力环境下）全身几乎相同的平均血压相反。这是由于动脉树的几何形状以及动脉壁可扩张性特性的区域差异所致。一方面，与心脏左心室做功相对的血压水平是中心压力；另一方面，位于主动脉弓和颈动脉分叉处的动脉压力感受器部位的动脉搏动性调节着心脏和外周阻力的交感神经与迷走神经控制。因此，确定这种中心脉压的变化对于了解抛物线飞行期间超重或失重状态下的心血管血液动力学至关重要。本研究的目的是在抛物线飞行期间无创评估颈动脉搏动性和力学特性。
