[麻醉大鼠抛物线飞行过程中颈总动脉血流的测量]

[Measurement of the common carotid arterial flow during parabolic flight in the anesthetized rat].

作者信息

Yamasaki M, Shimizu T, Nagayama T, Waki H, Wago H, Ohkouch T, Katahira K, Kaneko M, Torita K, Yamagata M, Shinnya K, Kanazawa M, Nemoto M, Mihara H, Ohkoshi S, Suzuki T, Tamura M, Satoh M, Tan-no M, Nagaoka S, Mukai C, Uemura M

机构信息

Department of Physiology, Fukushima Medical College.

出版信息

Biol Sci Space. 1996 Oct;10(3):190-1.

PMID:11540344

Abstract

To measure the blood flow of a common carotid artery (CCA) during parabolic flight in the rat, we developed an animal double hold box (ADHB) made of styrene expanded form for the anesthetized rat to keep the animal at a proper posture in an aircaft. Twelve anesthetized rats weighing 291-342 g were surgically operated to mount a ultrasound flowmeter probe (1 mm size,1RS:Transonic Systems Inc.) around the right CCA and to insert a catheter into the right axillar artery for blood pressure measurement. These animals were held comfortably in ADHBs which were placed on the rack installed in the aircraft (MU-300). A total of 27 parabolic flights was performed and the blood flow was measured accurately in 9 rats. This special animal holding facility is useful for various types of animal experiments in an aircraft.

摘要

为了测量大鼠在抛物线飞行过程中颈总动脉（CCA）的血流，我们开发了一种由发泡聚苯乙烯制成的动物双固定箱（ADHB），用于使麻醉后的大鼠在飞机上保持适当姿势。对12只体重291 - 342克的麻醉大鼠进行手术，在右侧颈总动脉周围安装超声流量计探头（尺寸为1毫米，型号1RS：Transonic Systems Inc.），并在右侧腋动脉插入导管以测量血压。这些动物被舒适地安置在放置于飞机（MU - 300）上安装的架子上的动物双固定箱中。总共进行了27次抛物线飞行，其中9只大鼠的血流被准确测量。这种特殊的动物固定设施对于在飞机上进行的各种类型动物实验很有用。