植物生长稳态由拟南芥BON1和BAP1基因控制。
Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes.
作者信息
Hua J, Grisafi P, Cheng S H, Fink G R
机构信息
Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.
出版信息
Genes Dev. 2001 Sep 1;15(17):2263-72. doi: 10.1101/gad.918101.
Abstract
Wild-type Arabidopsis plants maintain a relatively constant size over a wide range of temperatures. Here we show that this homeostasis requires the BONZAI1 (BON1) gene because bon1 null mutants make miniature fertile plants at 22 degrees C but have wild-type appearance at 28 degrees C. The expression of BON1 and a BON1-associated protein (BAP1) is modulated by temperature. Thus BON1 and BAP1 may have a direct role in regulating cell expansion and cell division at lower temperatures. BON1 contains a Ca(2+)-dependent phospholipid-binding domain and is associated with the plasma membrane. It belongs to the copine gene family, which is conserved from protozoa to humans. Our data suggest that this gene family may function in the pathway of membrane trafficking in response to external conditions.
摘要
野生型拟南芥植株在很宽的温度范围内能保持相对恒定的大小。我们在此表明，这种稳态需要BONZAI1（BON1）基因，因为bon1缺失突变体在22摄氏度时形成矮小的可育植株，但在28摄氏度时具有野生型外观。BON1和一种与BON1相关的蛋白（BAP1）的表达受温度调节。因此，BON1和BAP1可能在较低温度下调节细胞扩张和细胞分裂中具有直接作用。BON1含有一个依赖Ca(2+)的磷脂结合结构域，并与质膜相关。它属于从原生动物到人类都保守的联蛋白基因家族。我们的数据表明，这个基因家族可能在响应外部条件的膜运输途径中发挥作用。
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