用快速电子束和伽马射线辐照土豆以控制发芽的毒理学和卫生学调查。

Toxicologic and hygienic investigation of potatoes irradiated with a beam of fast electrons and gamma-rays to control sprouting.

作者信息

Zajcev A N, Shillinger J I, Kamaldinova Z M, Osipova I N

出版信息

Toxicology. 1975 Jul;4(3):267-74. doi: 10.1016/0300-483x(75)90049-9.

Abstract

Potatoes exposed either to gamma-rays at a dose of 20 krad, or irradiated with a beam of fast electrons at a dose of 30 krad to inhibit the sprouting of tubers, were studied for mutagenic effects. Toxic action and influence on the fertility were also investigated. Extracts of irradiated potatoes (10 krad gamma-rays), stored and then boiled, were also studied for their mutagenic effects. The induction of dominant lethal mutations (DLM) was used as indicator of mutagenic action of potatoes in male rats, that of the extracts of potatoes in male mice. Experimental animals (white rats) were fed with irradiated potatoes. Neither a toxic, nor a mutagenic action was found. Oral treatment of male mice with extracts of irradiated potatoes also did not increase the frequency of DLM in male mice.

摘要

研究了用20千拉德剂量的γ射线照射或用30千拉德剂量的快电子束辐照以抑制块茎发芽的马铃薯的诱变效应。还研究了其毒性作用和对生育能力的影响。对经10千拉德γ射线辐照、储存后再煮熟的马铃薯提取物也进行了诱变效应研究。在雄性大鼠中，显性致死突变（DLM）的诱导用作马铃薯诱变作用的指标，在雄性小鼠中则以马铃薯提取物的诱变作用为指标。给实验动物（白鼠）喂食辐照过的马铃薯。未发现有毒性作用或诱变作用。用辐照过的马铃薯提取物对雄性小鼠进行口服处理，也未增加雄性小鼠中DLM的发生率。