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辐照马铃薯和绿原酸的致突变性研究;大鼠微核试验

Mutagenicity studies on irradiated potatoes and chlorogenic acid; micronucleus test in rats.

作者信息

Hossain M M, Huismans J W, Diehl J F

出版信息

Toxicology. 1976 Aug-Sep;6(2):243-51. doi: 10.1016/0300-483x(76)90026-3.

Abstract

The micronucleus test was used to study possible mutagenic effects of (1) Irradiated potatoes extracted (a) immediately and (b) after 24-h storage following irradiation; (2) Irradiated and unirradiated chlorogenic acid; and (3) Trenimon. It was observed that irradiated potatoes (groups 1 a, b) and chlorogenic acid (group 2) did not cause mutagenic effects in the bone-marrow cells of rats. The Trenimon group (group 3), which was used as the positive control group, did show significant mutagenic effects.

摘要

微核试验用于研究以下物质的潜在诱变作用

(1)辐照马铃薯,分别于辐照后(a)立即提取以及(b)储存24小时后提取;(2)辐照和未辐照的绿原酸;(3)速灭磷。结果观察到,辐照马铃薯(第1组a、b)和绿原酸(第2组)对大鼠骨髓细胞未产生诱变作用。用作阳性对照组的速灭磷组(第3组)确实显示出显著的诱变作用。

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