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[神经移植的生物学基础]

[Biological foundations for neurotransplantation].

作者信息

Aleksandrova M A

机构信息

Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow, 119991 GSP-1, Russia.

出版信息

Ontogenez. 2001 Mar-Apr;32(2):106-13.

Abstract

A review of the mechanisms underlying cytogenesis and of the nervous tissues, the role of microenvironment, cell interactions in differentiation, and plastic rearrangements in the mammalian brain after transplantation of the embryonic nervous tissue. A common concept has been proposed, which unites biological processes involved in neurotransplantation and may serve as a theoretical base for the formation of ideas on pathways of differentiation of the nervous tissue, stimulation of compensatory processes and regeneration in the developing and pathological brain.

摘要

对细胞发生的潜在机制、神经组织、微环境的作用、分化中的细胞相互作用以及胚胎神经组织移植后哺乳动物大脑中的可塑性重排进行综述。提出了一个共同的概念,该概念将神经移植中涉及的生物学过程统一起来,并可作为形成关于神经组织分化途径、刺激发育中和病理状态下大脑的代偿过程及再生的思路的理论基础。

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