Wood C
Reprod Fertil Dev. 2001;13(1):91-3. doi: 10.1071/rd00059.
Embryo splitting may be used to increase the potential fertility of couples requiring IVF. Using cattle as a model, it is possible to increase pregnancy rates from 70% per transfer of good quality in-vivo-produced embryos, to 110% by transferring the two demi-embryos resulting from the bisection of one embryo. The 30-40% greater chance of conception would reduce costs for the government, health authorities and patients, and reduce stress, time and complications for women having IVF treatment. Embryo splitting may also provide donor embryos for infertile couples that cannot conceive naturally or with IVF. The shortage of children for adoption and donor embryos may be overcome by the production of demi-embryos.
胚胎分割可用于提高需要体外受精的夫妇的潜在生育能力。以牛作为模型,将优质体内产生的胚胎每次移植的妊娠率从70%提高到通过移植由一个胚胎二等分产生的两个半胚胎后的110%是可能的。受孕几率提高30%-40%将降低政府、卫生当局和患者的成本,并减少接受体外受精治疗的女性的压力、时间和并发症。胚胎分割还可为无法自然受孕或通过体外受精受孕的不育夫妇提供供体胚胎。通过生产半胚胎,可克服收养儿童和供体胚胎短缺的问题。