流感病毒的温度敏感突变体。VIII. A型流感病毒（H3N2）温度敏感突变体的遗传与生物学特性及其互补群的划分 - Suppr

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Temperature-sensitive mutants of influenza. VIII. Genetic and biological characterization of TS mutants of influenza virus A (H3N2) and their assignment to complementation groups.

作者信息

Spring S B, Nusinoff S R, Tierney E L, Richman D D, Murphy B R, Chanock R M

出版信息

Virology. 1975 Aug;66(2):542-50. doi: 10.1016/0042-6822(75)90226-3.

DOI:10.1016/0042-6822(75)90226-3

PMID:1154652

Abstract

摘要

相似文献

Temperature-sensitive mutants of influenza. VIII. Genetic and biological characterization of TS mutants of influenza virus A (H3N2) and their assignment to complementation groups.流感病毒的温度敏感突变体。VIII. A型流感病毒（H3N2）温度敏感突变体的遗传与生物学特性及其互补群的划分

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Temperature sensitive mutants of influenza virus. IX. Genetic and biological characterization of TS-1[E] lesions when transferred to a 1972 (H3N2) influenza A virus.流感病毒的温度敏感突变体。IX. 当TS-1[E]损伤转移至1972年甲型（H3N2）流感病毒时的遗传学和生物学特征

Virology. 1975 Aug;66(2):551-62. doi: 10.1016/0042-6822(75)90227-5.

Temperature-sensitive mutants of influenza virus. VI. Transfer of TS lesions from the Asian subtype of influenza A virus (H2N2) to the Hong Kong subtype (H3N2).甲型流感病毒的温度敏感突变体。VI. 甲型流感病毒亚洲亚型（H2N2）的温度敏感损伤向香港亚型（H3N2）的转移。

Virology. 1975 Aug;66(2):522-32. doi: 10.1016/0042-6822(75)90224-x.

Temperature-Sensitive mutants of influenza virus. VII. Transfer of the TS-1[E] lesions to a wild-type influenza A virus with the HON1 surface antigens.流感病毒的温度敏感突变体。VII. 将TS-1[E]损伤转移至具有HON1表面抗原的野生型甲型流感病毒。

Virology. 1975 Aug;66(2):533-41. doi: 10.1016/0042-6822(75)90225-1.

Temperature-sensitive mutants of influenza A virus. Transfer of the two ts-1A2 ts lesions present in the Udorn/72-ts-1A2 donor virus to the influenza A/Alaska/6/77 (H3N2) wild type virus.甲型流感病毒的温度敏感突变体。将存在于乌栋/72-ts-1A2供体病毒中的两个ts-1A2 ts损伤转移至甲型流感病毒/阿拉斯加/6/77（H3N2）野生型病毒。

Arch Virol. 1980;65(2):175-86. doi: 10.1007/BF01317329.

Cold adapted variants of influenza A. II. Comparison of the genetic and biological properties of ts mutants and recombinants of the cold adapted A/AA/6/60 strain.甲型流感的冷适应变种。II. 冷适应A/AA/6/60株的温度敏感突变体和重组体的遗传及生物学特性比较

Arch Virol. 1977;55(3):233-46. doi: 10.1007/BF01319909.

Temperature-sensitive mutants of influenza virus. XV. The genetic and biological characterization of a recombinant influenza virus containing two ts lesions produced by mating two complementing, single lesion ts mutants.流感病毒的温度敏感突变体。十五、一种重组流感病毒的遗传和生物学特性，该重组病毒含有通过将两个互补的单损伤温度敏感突变体杂交产生的两个温度敏感损伤。

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Temperature-sensitive mutants of influenza A/Udorn/72 (H3N2) virus. III. Genetic analysis of temperature-dependent host range mutants.甲型流感病毒A/Udorn/72（H3N2）的温度敏感突变体。III. 温度依赖性宿主范围突变体的遗传分析

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Temperature-sensitive mutants of influenza A virus: transfer of the two temperature-sensitive lesions in the Udorn/72-ts-1A2 virus to the A2Hong Kong/123/77 (H1N1) wild-type virus.甲型流感病毒的温度敏感突变体：将乌东/72-ts-1A2病毒中的两个温度敏感损伤转移至A2香港/123/77（H1N1）野生型病毒。

Infect Immun. 1980 Jun;28(3):792-8. doi: 10.1128/iai.28.3.792-798.1980.

Naturally occurring temperature-sensitive influenza A viruses of the H1N1 and H3N2 subtypes.自然产生的H1N1和H3N2亚型温度敏感型甲型流感病毒。

J Gen Virol. 1980 Jun;48(Pt 2):383-9. doi: 10.1099/0022-1317-48-2-383.

引用本文的文献

Sequential addition of temperature-sensitive missense mutations into the PB2 gene of influenza A transfectant viruses can effect an increase in temperature sensitivity and attenuation and permits the rational design of a genetically engineered live influenza A virus vaccine.将温度敏感型错义突变依次添加到甲型流感转染病毒的PB2基因中，可提高温度敏感性并实现减毒，从而有助于合理设计基因工程甲型流感活病毒疫苗。

J Virol. 1995 Oct;69(10):5969-77. doi: 10.1128/JVI.69.10.5969-5977.1995.

Arch Virol. 1980;65(2):175-86. doi: 10.1007/BF01317329.

Infect Immun. 1980 Jun;28(3):792-8. doi: 10.1128/iai.28.3.792-798.1980.

Production and level of genetic stability of an influenza A virus temperature-sensitive mutant containing two genes with ts mutations.一种含有两个带有温度敏感（ts）突变基因的甲型流感病毒温度敏感突变株的产生及其遗传稳定性水平

Infect Immun. 1982 Jul;37(1):235-42. doi: 10.1128/iai.37.1.235-242.1982.

Studies with some influenza B viruses in cell cultures, hamsters and hamster tracheal organ cultures.

Med Microbiol Immunol. 1981;169(3):179-86. doi: 10.1007/BF02123591.

Identification of the defective genes in three mutant groups of influenza virus.流感病毒三个突变组中缺陷基因的鉴定。

J Virol. 1977 Mar;21(3):1196-204. doi: 10.1128/JVI.21.3.1196-1204.1977.

Use of temperature-sensitive mutants of influenza A virus as live virus vaccine strains. Evaluation in laboratory animals, adults and children.甲型流感病毒温度敏感突变株作为活病毒疫苗株的应用。在实验动物、成人和儿童中的评估。

Postgrad Med J. 1976 Jun;52(608):381-8. doi: 10.1136/pgmj.52.608.381.

Temperature-sensitive mutants of influenza A virus: production and characterization of A/Victoria/3/75-ts-1[E] recombinants.甲型流感病毒温度敏感突变体：A/维多利亚/3/75-ts-1[E]重组体的产生与特性分析

Infect Immun. 1978 Jun;20(3):665-70. doi: 10.1128/iai.20.3.665-670.1978.

Arch Virol. 1977;55(3):233-46. doi: 10.1007/BF01319909.

Growth of some attenuated influenza viruses in hamster tracheal organ cultures.一些减毒流感病毒在仓鼠气管器官培养物中的生长情况。

Med Microbiol Immunol. 1978 Nov 17;166(1-4):141-50. doi: 10.1007/BF02121143.

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