Barquist E, Brown M, Cohn S, Lundy D, Jackowski J
Department of Surgery, Division of Trauma and Critical Care, University of Miami, Miami, FL, USA.
Crit Care Med. 2001 Sep;29(9):1710-3. doi: 10.1097/00003246-200109000-00009.
Critically ill trauma patients frequently require prolonged endotracheal intubation and ventilator support. After extubation, swallowing difficulties may exist in < or = 50% of patients. We sought to determine whether performing a swallowing evaluation would reduce the incidence of postextubation aspiration and subsequent pneumonia.
Randomized, prospective clinical trial of fiberoptic endoscopic evaluation of swallowing (FEES) vs. routine clinical management in patients after prolonged intubation.
Seventy patients who were intubated for > 48 hrs were randomized. FEES examinations were performed within 24 +/- 2 hrs after extubation. Silent aspiration was defined as the appearance of liquid or puree bolus below the true vocal cords without coughing during a FEES examination. Clinical aspiration was defined as the removal of enteral content from below the vocal cords, usually during endotracheal tube placement.
There were five episodes of aspiration and pneumonia in the FEES group (14%, two silent) and two in the clinical group (6%, not significant, Fisher exact test). Patients aged > 55 yrs and those with vallecular stasis on FEES examination were at significantly higher risk of postextubation aspiration. All patients with pneumonia had an associated aspiration episode.
Patients with prolonged orotracheal intubation are at risk of aspiration after extubation. The addition of a FEES examination did not change the incidence of aspiration or postextubation pneumonia.
重症创伤患者常常需要长时间气管插管和呼吸机支持。拔管后,多达50%的患者可能存在吞咽困难。我们试图确定进行吞咽评估是否会降低拔管后误吸及随后肺炎的发生率。
对长时间插管后的患者进行纤维喉镜吞咽功能评估(FEES)与常规临床管理的随机、前瞻性临床试验。
70例插管超过48小时的患者被随机分组。在拔管后24±2小时内进行FEES检查。隐性误吸定义为在FEES检查期间,真声带下方出现液体或泥状食团且无咳嗽。临床误吸定义为通常在气管插管放置期间从声带下方清除肠内物质。
FEES组有5例误吸和肺炎发作(14%,2例隐性),临床组有2例(6%,无显著差异,Fisher精确检验)。年龄大于55岁的患者以及FEES检查发现会厌谷淤滞的患者拔管后误吸风险显著更高。所有肺炎患者均伴有误吸发作。
长时间经口气管插管患者拔管后有发生误吸的风险。增加FEES检查并未改变误吸或拔管后肺炎的发生率。