Pisarev V V, Miagkova M A, Briun E A, Koporov S G, Eremin S A, Trubacheva Zh N, Abramenko T V
Sud Med Ekspert. 2001 Mar-Apr;44(2):43-6.
Competitive solid-phase enzyme immunoassay of gidasepam (a benzodiazepine) in the urine with chemiluminescent detection has been developed. The sensitivity of analysis for gidasepam is 10 ng/ml. Comparative measurements of benzodiazepines in the urine of patients abusing these agents by polarization fluorescence and the proposed method showed good coincidence of the results. The results demonstrate the possibility of using this method in medicine and narcology in combination with other instrumental methods.
已开发出一种采用化学发光检测法对尿液中吉达西泮(一种苯二氮䓬类药物)进行竞争性固相酶免疫测定的方法。吉达西泮的分析灵敏度为10纳克/毫升。通过偏振荧光法和所提出的方法对滥用这些药物患者尿液中的苯二氮䓬类药物进行对比测量,结果显示吻合度良好。这些结果证明了该方法与其他仪器方法相结合应用于医学和麻醉学的可能性。