Spaić M, Minić Lj, Djitić R, Lukić Z, Tadić R
Vojnosanit Pregl. 2001 May-Jun;58(3):249-54.
The late outcome of implantation of the vascular omental pedicle on the injured spinal cord performed in 7 patients to improve functional recovery through revascularization of the injured cord tissue is reported. All the patients were reoperated at the same spinal level 2-5 years after the omental pedicle implantation for the treatment of chronic neuropathic spinal pain by employing DREZ (Dorsal Root Entry Zone lesion) surgery. From the technical standpoint it was necessary to mobilize the implanted omental pedicle from the cord surface to provide the access to dorsolateral cord sulcus for the DREZ operation. Mobilization of the omental pedicle provided unique opportunity to observe omental-cord contact surface (omentomielosinangiosis) that is believed to stimulate revascularization of the cord tissue. In our report particular attention was paid to the specificity of the omental-cord contact surface and the late tissue changes of the cord as well as omental tissue knowing the fact that the capacity of omental tissue to stimulate neoangiogenesis still represents the actual doubt in neurobiological theory and practice. Detailed analysis of the actual neurological condition of these patients compared to neurological condition assessed before the implantation of the pediculated-vascular omental graft revealed neither sensory nor motoric improvement (in the postimplantation period). The effect of DREZ surgery of the chronic neuropathic spinal pain was not a topic of this report.
报告了7例患者接受血管化网膜蒂植入损伤脊髓手术的远期结果,该手术旨在通过损伤脊髓组织的血管再生来改善功能恢复。所有患者在网膜蒂植入术后2至5年,于同一脊髓节段再次手术,采用脊髓背根入髓区(DREZ)手术治疗慢性神经性脊柱疼痛。从技术角度看,有必要将植入的网膜蒂从脊髓表面游离,以便为DREZ手术提供进入脊髓背外侧沟的通道。网膜蒂的游离提供了独特的机会来观察网膜 - 脊髓接触面(网膜脊髓血管生成),据信这会刺激脊髓组织的血管再生。在我们的报告中,特别关注了网膜 - 脊髓接触面的特异性以及脊髓和网膜组织的晚期组织变化,因为网膜组织刺激新生血管生成的能力在神经生物学理论和实践中仍然存在实际疑问。与带血管网膜移植植入术前评估的神经状况相比,对这些患者实际神经状况的详细分析显示(在植入后期)感觉和运动功能均未改善。本报告未涉及DREZ手术治疗慢性神经性脊柱疼痛的效果。