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远程后装高剂量率近距离放射治疗源传输时间的测量。

Measurement of transit time of a remote after-loading high dose rate brachytherapy source.

作者信息

Sahoo N

机构信息

Department of Radiation Oncology, Albany Medical College, New York 12208, USA.

出版信息

Med Phys. 2001 Aug;28(8):1786-90. doi: 10.1118/1.1386779.

DOI:10.1118/1.1386779
PMID:11548950
Abstract

Quantification of transit time of a remote after-loading high dose rate (HDR) brachytherapy source is important both for accurate treatment planning and for quality assurance checks. In this investigation, an HDR-1000 well ionization chamber and a precision electrometer are used to measure the transit time of the Ir-192 source of a Nucletron Micro-Selectron HDR brachytherapy unit. The charge generated both during source dwelling at a selected position in an endobronchial catheter inserted into the chamber and during source travel to this position from another location at a distance of 0.5 to 10 cm from it was measured. A linear regression analysis of the measured charge as a function of dwell time was made. The interdwell position transit time was calculated from the ratio of the charge intercept and the slope of the straight line obtained from the regression analysis. The values of the effective transit time, which is a combination of interdwell position transit time and dwell time error of the after-loading unit, were found to be 0.03 and 0.45 s for 0.5 and 10 cm separation between two dwell positions, respectively. The average time for 1 cm travel of the source between two dwell positions was found to be 0.022 s, resulting in an average speed of 45.5 cm/s. This simple procedure has the potential to be utilized for routine quality assurance check of the interdwell position transit time of any remote after-loading HDR brachytherapy source.

摘要

远程后装高剂量率(HDR)近距离放射治疗源的传输时间量化对于精确的治疗计划和质量保证检查都很重要。在本研究中,使用一个HDR - 1000型井型电离室和一个精密静电计来测量Nucletron Micro - Selectron HDR近距离放射治疗装置的铱 - 192源的传输时间。测量了源在插入电离室的支气管内导管中选定位置驻留期间以及源从距离该位置0.5至10 cm的另一位置移动到该位置期间产生的电荷。对测量的电荷作为驻留时间的函数进行了线性回归分析。根据电荷截距与回归分析所得直线斜率的比值计算驻留位置间的传输时间。有效传输时间是驻留位置间传输时间与后装装置驻留时间误差的组合,对于两个驻留位置之间0.5 cm和10 cm的间距,其值分别为0.03 s和0.45 s。发现源在两个驻留位置之间移动1 cm的平均时间为0.022 s,平均速度为45.5 cm/s。这个简单的程序有可能用于对任何远程后装HDR近距离放射治疗源的驻留位置间传输时间进行常规质量保证检查。

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