Gaillard Y, Pepin G
Laboratoire d'Expertises TOXLAB, Paris, France.
J Anal Toxicol. 2001 Sep;25(6):481-5. doi: 10.1093/jat/25.6.481.
We report two fatal poisonings due to the ingestion of plant material. The two deceased were discovered in the water of a mountain lake about one month after the postmortem immersion of the corpses. Macroscopic examination of the stomachs revealed the presence of a very large number of small blackish granules, which were later identified as seeds of a Veratrum species. Veratridine and cevadine were identified and quantitated by high-performance liquid chromatography-electrospray ionization-mass spectrometry. Measured blood concentrations were 0.17 and 0.40 ng/mL for veratridine and 0.32 and 0.48 ng/mL for cevadine. The absence of other toxic substance led to the assumption that this massive ingestion was the cause of death, although the circumstances surrounding intake remained unknown.
我们报告了两起因摄入植物材料导致的致命中毒事件。两名死者的尸体在死后浸泡于山间湖泊水中约一个月后被发现。对胃部进行宏观检查发现有大量黑色小颗粒，后来鉴定为藜芦属植物的种子。通过高效液相色谱 - 电喷雾电离 - 质谱法对藜芦定和瑟瓦定进行了鉴定和定量。测得的藜芦定血药浓度分别为0.17和0.40 ng/mL，瑟瓦定血药浓度分别为0.32和0.48 ng/mL。由于未发现其他有毒物质，因此推测大量摄入这些物质是死亡原因，尽管摄入的具体情况仍不清楚。
