Schwartz J N, Kong Y, Hackel D B, Bartel A G
Am J Cardiol. 1975 Aug;36(2):174-8. doi: 10.1016/0002-9149(75)90522-6.
The accuracy of coronary cineangiography in predicting the degree of stenosis in coronary arteries was evaluated by comparing autopsy and premortem cineangiographic findings in 25 patients. Coronary cineangiograms and autopsy specimens were reviewed independently by two cardiologists and two pathologists. Identical diagrams dividing the cononary arteries into 12 segments were used by both groups to record the location and degree of stenosis observed. Cineangiographic findings were in agreement with pathologic findings (less than 25 percent difference in cross-sectional luminal area) in 178 (79 percent) of the 226 segments examined, but overestimated the degree of stenosis in 13 (6 percent) and underestimated it in 34 (15 percent). Thus, cineangiography appears to be a reliable tool in evaluating coronary artery disease. When diagnostic errors are made, they are usually underestimations of the degree of disease; common causes of error are circumferential stenosis, eccentric lesions, obstruction of view by artifical valves and poor opacification due to severe proximal stenosis.
通过比较25例患者的尸检结果和生前冠状动脉造影结果，评估了冠状动脉造影在预测冠状动脉狭窄程度方面的准确性。两名心脏病专家和两名病理学家分别独立审查了冠状动脉造影图像和尸检标本。两组均使用相同的将冠状动脉分为12段的示意图来记录观察到的狭窄位置和程度。在检查的226个节段中，178个（79%）的冠状动脉造影结果与病理结果一致（横断面管腔面积差异小于25%），但有13个（6%）节段高估了狭窄程度，34个（15%）节段低估了狭窄程度。因此，冠状动脉造影似乎是评估冠状动脉疾病的可靠工具。当出现诊断错误时，通常是对疾病程度的低估；常见的错误原因包括环形狭窄、偏心病变、人工瓣膜遮挡视野以及严重近端狭窄导致的造影剂充盈不佳。
