Arnett E N, Isner J M, Redwood D R, Kent K M, Baker W P, Ackerstein H, Roberts W C
Ann Intern Med. 1979 Sep;91(3):350-6. doi: 10.7326/0003-4819-91-3-350.
Of 10 patients with fatal coronary heart disease undergoing coronary angiography 0 to 69 d (average, 21) before necropsy, the amount of narrowing in 61 coronary arteries observed angiographically (diameter reduction) during life by three angiographers was compared with that observed histologically (cross-sectional area) at necropsy. No overestimations of the degree of narrowing were made angiographically. Of 11 coronary arteries or their subdivisions narrowed 0 to 50% in cross-sectional area histologically, none were underestimated angiographically; of eight narrowed 51% to 75% histologically, seven had been underestimated, and of 42 narrowed 76% to 100% histologically, 17 were underestimated angiographically. The coronary atherosclerotic plaquing was diffuse (greater than 25% cross-sectional area narrowing) in 90% of 467 five-millimetre segments of coronary artery examined (24 cm per patient), and this diffuseness of the atherosclerotic process seems to be the major reason for angiographic underestimation of coronary narrowings.
在尸检前0至69天（平均21天）接受冠状动脉造影的10例致命性冠心病患者中，比较了三位血管造影师在生前通过血管造影观察到的61条冠状动脉的狭窄程度（直径减小）与尸检时组织学观察到的狭窄程度（横截面积）。血管造影未对狭窄程度进行高估。在组织学上横截面积狭窄0至50%的11条冠状动脉或其分支中，血管造影均未低估；在组织学上狭窄51%至75%的8条冠状动脉中，7条被低估，在组织学上狭窄76%至100%的42条冠状动脉中，17条被血管造影低估。在检查的467个5毫米冠状动脉节段（每位患者24厘米）中，90%的冠状动脉粥样硬化斑块是弥漫性的（横截面积狭窄大于25%），这种动脉粥样硬化过程的弥漫性似乎是血管造影低估冠状动脉狭窄的主要原因。
