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偏头痛的诊断与治疗:美国偏头痛研究II的结果

Migraine diagnosis and treatment: results from the American Migraine Study II.

作者信息

Lipton R B, Diamond S, Reed M, Diamond M L, Stewart W F

机构信息

Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.

出版信息

Headache. 2001 Jul-Aug;41(7):638-45. doi: 10.1046/j.1526-4610.2001.041007638.x.

Abstract

OBJECTIVE

A population-based survey was conducted in 1999 to describe the patterns of migraine diagnosis and medication use in a representative sample of the US population and to compare results with a methodologically identical study conducted 10 years earlier.

METHODS

A survey mailed to a panel of 20 000 US households identified 3577 individuals with severe headache meeting a case definition for migraine based on the International Headache Society (IHS) criteria. Those with severe headache answered questions regarding physician diagnosis and use of medications for headache as well as headache-related disability.

RESULTS

A physician diagnosis of migraine was reported by 48% of survey participants who met IHS criteria for migraine in 1999, compared with 38% in 1989. A total of 41% of IHS-defined migraineurs used prescription drugs for headaches in 1999, compared with 37% in 1989. The proportion of IHS-defined migraineurs using only over-the-counter medications to treat their headaches was 57% in 1999, compared with 59% in 1989. In 1999, 37% of diagnosed and 21% of undiagnosed migraineurs reported 1 to 2 days of activity restriction per episode (P<.001); 38% of diagnosed and 24% of undiagnosed migraineurs missed at least 1 day of work or school in the previous 3 months (P<.001); 57% of diagnosed and 45% of undiagnosed migraineurs experienced at least a 50% reduction in work/school productivity (P<.001).

CONCLUSIONS

Diagnosis of migraine has increased over the past decade. Nonetheless, approximately half of migraineurs remain undiagnosed, and the increased rates of diagnosis of migraine have been accompanied by only a modest increase in the proportion using prescription medicines. Migraine continues to cause significant disability whether or not there has been a physician diagnosis. Given the availability of effective treatments, public health initiatives to improve patterns of care are warranted.

摘要

目的

1999年开展了一项基于人群的调查,以描述美国人群代表性样本中偏头痛的诊断模式和药物使用情况,并将结果与10年前进行的方法相同的研究进行比较。

方法

向一个由20000户美国家庭组成的小组邮寄调查问卷,根据国际头痛协会(IHS)标准,识别出3577名符合偏头痛病例定义的严重头痛患者。患有严重头痛的患者回答了有关医生诊断、头痛药物使用以及头痛相关残疾的问题。

结果

1999年符合IHS偏头痛标准的调查参与者中,48%报告有医生诊断的偏头痛,而1989年为38%。1999年,IHS定义的偏头痛患者中共有41%使用处方药治疗头痛,1989年为37%。1999年,IHS定义的仅使用非处方药治疗头痛的偏头痛患者比例为57%,1989年为59%。1999年,37%的已诊断偏头痛患者和21%的未诊断偏头痛患者报告每次发作有1至2天的活动受限(P<0.001);38%的已诊断偏头痛患者和24%的未诊断偏头痛患者在过去3个月中至少缺课或误工1天(P<0.001);57%的已诊断偏头痛患者和45%的未诊断偏头痛患者工作/学习效率至少降低了50%(P<0.001)。

结论

在过去十年中,偏头痛的诊断有所增加。尽管如此,仍有大约一半的偏头痛患者未被诊断出来,偏头痛诊断率的提高仅伴随着使用处方药比例的适度增加。无论是否有医生诊断,偏头痛都会导致严重残疾。鉴于有有效的治疗方法,开展公共卫生倡议以改善治疗模式是有必要的。

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