Kakomy A
Anaesth Resusc Intensive Ther. 1975 Jan-Mar;3(1):3-14.
The author studied the morphological changes developing in the tracheobronchial mucosa following a surgical tracheal fistula. The experiments were carried out on 19 dogs which were divided into 2 groups. Group I included 10 dogs, in which specimens were obtained by bronchoscopy; in group II, 9 dogs, specimens were obtained directly. Histological examinations were carried out by Gomori's reaction and hematoxylin-eosin staining method. Histo-chemical tests included PAS reaction and alcian blue stain. The results showed that after 24 hours morphological changes mainly involved the tracheal mucosa and their characteristic feature was the variety of forms of lesions of the epithelium covering the mucosa. The longer the duration of the fistula the more these changes increased in intensity and involved further parts of the tracheobronchial tree. The author also took into account the living conditions in the kennels where the dogs were kept following the tracheostomy. The changes observed were compared with those reported by other authors and the correlation between the occurrence of these changes and the environmental conditions and length of breathing through the surgically produced fistula was analysed.
作者研究了气管造瘘术后气管支气管黏膜发生的形态学变化。实验在19只狗身上进行，这些狗被分为两组。第一组包括10只狗，通过支气管镜获取标本；第二组有9只狗，直接获取标本。组织学检查采用Gomori反应和苏木精-伊红染色法。组织化学测试包括PAS反应和阿尔辛蓝染色。结果显示，24小时后形态学变化主要累及气管黏膜，其特征是覆盖黏膜的上皮病变形式多样。瘘管存在的时间越长，这些变化的强度增加得越多，并且累及气管支气管树的更多部位。作者还考虑了气管切开术后狗所饲养犬舍的生活条件。将观察到的变化与其他作者报告的变化进行比较，并分析了这些变化的发生与环境条件以及通过手术造成的瘘管呼吸时间长短之间的相关性。
