为什么十二指肠胆管塑料支架会堵塞？对100例连续患者的临床和病理研究。
Why do bilioduodenal plastic stents become occluded? A clinical and pathological investigation on 100 consecutive patients.
作者信息
Weickert U, Venzke T, König J, Janssen J, Remberger K, Greiner L
机构信息
Dept. of Medicine II (Gastroenterology), Wuppertal Clinical Center, University of Witten/Herdecke, Germany.
出版信息
Endoscopy. 2001 Sep;33(9):786-90. doi: 10.1055/s-2001-16519.
BACKGROUND AND STUDY AIMS
The main complication associated with biliary stenting is stent occlusion. This study tested the hypothesis that bilioduodenal reflux may play a crucial role in stent clogging.
PATIENTS AND METHODS
Plastic stents in 100 consecutive patients with various biliary disorders were investigated macroscopically and cytologically.
RESULTS
In 37 patients with elective stent extraction, the only risk factor for stent occlusion was the duration of stenting. Plant material was found as a consequence of duodenobiliary reflux in 38 of the 89 stents with any stent content. In patients who had two stents, the stent content was identical in eight of 14 cases.
CONCLUSIONS
In addition to other mechanisms of biliary stent occlusion, duodenobiliary reflux appears to play an important role. A stent design capable of at least partly preventing this type of reflux might be of clinical benefit.
背景与研究目的
与胆道支架置入相关的主要并发症是支架堵塞。本研究检验了十二指肠胆管反流可能在支架堵塞中起关键作用这一假设。
患者与方法
对连续100例患有各种胆道疾病的患者所置入的塑料支架进行了宏观和细胞学研究。
结果
在37例择期取出支架的患者中，支架堵塞的唯一危险因素是支架置入时间。在89个有任何支架内容物的支架中，有38个发现有十二指肠胆管反流导致的植物性物质。在置入两个支架的患者中，14例中有8例支架内容物相同。
结论
除了胆道支架堵塞的其他机制外，十二指肠胆管反流似乎也起重要作用。一种能够至少部分防止此类反流的支架设计可能具有临床益处。
Zotero 插件