壮观链霉菌菌株产生的新型免疫抑制剂SNF4435C和D。II. 结构解析。
SNF4435C and D, novel immunosuppressants produced by a strain of Streptomyces spectabilis. II. Structure elucidation.
作者信息
Takahashi K, Tsuda E, Kurosawa K
机构信息
Research Institute of Life Science, Snow Brand Milk Products Co., Ltd., Tochigi, Japan.
出版信息
J Antibiot (Tokyo). 2001 Jul;54(7):548-53. doi: 10.7164/antibiotics.54.548.
SNF4435C and D are new immunosuppressants isolated from the culture broth of a strain of Streptomyces spectabilis. Their molecular formulas were determined as C28H31NO6 based on the HRFAB-MS analyses. The structures of SNF4435C and D were elucidated to be novel nitrophenyl pyrones having an intriguing tricyclic ring system and diastereoisomers of each other by spectroscopic analyses including various NMR measurements.
SNF4435C和D是从壮观链霉菌菌株的培养液中分离出的新型免疫抑制剂。基于高分辨快原子轰击质谱（HRFAB-MS）分析，它们的分子式被确定为C28H31NO6。通过包括各种核磁共振测量在内的光谱分析，SNF4435C和D的结构被阐明为具有一个有趣的三环系统的新型硝基苯基吡喃酮，且它们彼此为非对映异构体。
Zotero 插件