一种新的抗疱疹剂AH - 1763 IIa，由编号为1763的青色链霉菌菌株产生。
A new antiherpetic agent, AH-1763 IIa, produced by Streptomyces cyaneus strain no. 1763.
作者信息
Uyeda M, Yokomizo K, Ito A, Nakayama K, Watanabe H, Kido Y
机构信息
Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
出版信息
J Antibiot (Tokyo). 1997 Oct;50(10):828-32. doi: 10.7164/antibiotics.50.828.
A new antiherpetic agent, AH-1763 IIa, was isolated from the culture broth of strain No. 1763 identified as Streptomyces cyaneus. It was purified through column chromatographies of Diaion HP-10 and silica gel. The structure was determined to be 11-hydroxy-5-methyl-2-(2-hydroxy-1-methylpropyl)-4H-anthraceno [1,2-b]pyran-4,7,12-trione by several spectroscopic experiments, that is a new antibiotic belonging to pluramycin-group.
一种新型抗疱疹药物AH - 1763 IIa，是从被鉴定为青色链霉菌的1763号菌株的培养液中分离出来的。它通过Diaion HP - 10和硅胶柱色谱法进行纯化。通过几项光谱实验确定其结构为11 - 羟基 - 5 - 甲基 - 2 - (2 - 羟基 - 1 - 甲基丙基) - 4H - 蒽并[1,2 - b]吡喃 - 4,7,12 - 三酮，这是一种属于多杀菌素类的新型抗生素。
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