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可调式胃束带术与垂直束带胃成形术治疗病态肥胖的前瞻性随机对照研究

Prospective randomised comparison of adjustable gastric banding and vertical banded gastroplasty for morbid obesity.

作者信息

Nilsell K, Thörne A, Sjöstedt S, Apelman J, Pettersson N

机构信息

Department of Surgery, Karolinska Institute at Huddinge University Hospital, Stockholm, Sweden.

出版信息

Eur J Surg. 2001 Jul;167(7):504-9. doi: 10.1080/110241501316914876.

Abstract

OBJECTIVE

To compare the clinical results of adjustable gastric banding and vertical banded gastroplasty for morbid obesity.

DESIGN

Prospective randomised trial.

SETTING

University hospital, Sweden.

PATIENTS

59 morbidly obese patients, listed for obesity surgery.

INTERVENTIONS

Adjustable gastric banding (n = 29) or vertical banded gastroplasty (n = 30).

MAIN OUTCOME MEASURES

Weight loss, complications, need for revisional surgery, reflux symptoms and the patient's own evaluation.

RESULTS

Five years after surgery the mean (SEM) weight reduction for adjustable gastric banding was 43 (3.0) kg and for vertical banded gastroplasty 35 (4.8) kg. One patient in each group died of unrelated causes during follow-up and 3 and 2 patients, respectively, were lost to follow-up. One patient in the vertical banded group required reoperation for an anastomotic leak on the third postoperative day. A total of 3 patients in the adjustable group required reoperation and 11 in the vertical banded group.

CONCLUSIONS

Adjustable gastric banding carries a smaller risk of reoperation than vertical banded gastroplasty and the weight reduction is in the same order of magnitude.

摘要

目的

比较可调节胃束带术与垂直带状胃成形术治疗病态肥胖症的临床效果。

设计

前瞻性随机试验。

地点

瑞典大学医院。

患者

59例拟行肥胖症手术的病态肥胖患者。

干预措施

可调节胃束带术(n = 29)或垂直带状胃成形术(n = 30)。

主要观察指标

体重减轻、并发症、再次手术需求、反流症状及患者自身评价。

结果

术后5年,可调节胃束带术组平均(标准误)体重减轻43(3.0)kg,垂直带状胃成形术组为35(4.8)kg。随访期间每组各有1例患者死于非相关原因,分别有3例和2例患者失访。垂直带状胃成形术组有1例患者在术后第3天因吻合口漏需要再次手术。可调节胃束带术组共有3例患者需要再次手术,垂直带状胃成形术组有11例。

结论

与垂直带状胃成形术相比,可调节胃束带术再次手术的风险较小,且体重减轻幅度相当。

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