The biotransformation of 1-hexadecene to carcinogenic 1,2-epoxyhexadecane by hepatic microsomes.
作者信息
Watabe T, Yamada N
出版信息
Biochem Pharmacol. 1975 May 1;24(9):1051-3. doi: 10.1016/0006-2952(75)90445-1.
PMID:1156447
Abstract
摘要
相似文献
1
The biotransformation of 1-hexadecene to carcinogenic 1,2-epoxyhexadecane by hepatic microsomes.肝脏微粒体将1-十六碳烯生物转化为致癌物质1,2-环氧十六烷。
Biochem Pharmacol. 1975 May 1;24(9):1051-3. doi: 10.1016/0006-2952(75)90445-1.
2
Metabolism of the carcinogenic bifunctional olefin oxide, 4-vinyl-1-cyclohexene dioxide, by hepatic microsomes.肝脏微粒体对致癌性双功能环氧化烯烃4-乙烯基-1,2-环氧环己烷的代谢作用。
Biochem Pharmacol. 1976 Mar 1;25(5):601-2. doi: 10.1016/0006-2952(76)90395-6.
3
Fate of epoxides.环氧化物的命运
Adv Exp Med Biol. 1981;136 Pt A:39-52.
4
Metabolism of chrysene and phenanthrene to bay-region diol epoxides by rat liver enzymes.大鼠肝脏酶将屈和菲代谢为湾区二醇环氧化物。
Mol Pharmacol. 1981 Jan;19(1):168-78.
5
Hepatic and extrahepatic metabolism, in vitro, of an epoxide (8-(14) C-styrene oxide) in the rabbit.兔体内环氧物（8-(14)C-苯乙烯氧化物）的肝内和肝外代谢（体外实验）
Biochem Pharmacol. 1976 Jan 15;25(2):187-93. doi: 10.1016/0006-2952(76)90289-6.
6
Enzymatic hydration of butadiene monoxide and its importance in the metabolism of butadiene.一氧化丁二烯的酶促水合作用及其在丁二烯代谢中的重要性。
Adv Exp Med Biol. 1981;136 Pt A:437-44. doi: 10.1007/978-1-4757-0674-1_32.
7
Alphatic 3,4-epoxyalcohols. Metabolism by epoxide hydrase and mutagenic activity.脂肪族3,4-环氧醇。经环氧水解酶的代谢及致突变活性。
Biochim Biophys Acta. 1978 Dec 18;544(3):504-13. doi: 10.1016/0304-4165(78)90325-2.
8
Distinct rat hepatic microsomal epoxide hydrolases catalyze the hydration of cholesterol 5,6 alpha-oxide and certain xenobiotic alkene and arene oxides.不同的大鼠肝脏微粒体环氧化物水解酶催化胆固醇5,6α-氧化物以及某些外源性烯烃和芳烃氧化物的水化反应。
Arch Biochem Biophys. 1983 Feb 1;220(2):485-94. doi: 10.1016/0003-9861(83)90439-3.
9
Biotransformation of allylbenzene analogues in vivo and in vitro through the epoxide-diol pathway.
Xenobiotica. 1980 Oct;10(10):737-44. doi: 10.3109/00498258009033801.
10
The metabolic activation of chemical carcinogens.化学致癌物的代谢活化。
Br Med Bull. 1980 Jan;36(1):11-8. doi: 10.1093/oxfordjournals.bmb.a071607.
引用本文的文献
1
Irreversible binding of 3-14C-antipyrine to hepatic protein in vivo and in metabolizing liver microsomes.3-¹⁴C-安替比林在体内及代谢性肝微粒体中与肝蛋白的不可逆结合。
Naunyn Schmiedebergs Arch Pharmacol. 1977 Mar;297(1):105-10. doi: 10.1007/BF00508817.
Zotero 插件