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早期经口喂养对冠心病监护病房患者血浆游离脂肪酸浓度的影响。

Effect of early oral feeding on plasma free fatty acid concentrations in patients in a coronary care unit.

作者信息

Opie L H, Bruyneel K J, Kennelly B M

出版信息

Br Heart J. 1975 Jul;37(7):700-4. doi: 10.1136/hrt.37.7.700.

DOI:10.1136/hrt.37.7.700
PMID:1156477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC482860/
Abstract

Forty-two consecutive patients with acute myocardial infarction were studied over the first 3 days of their illness to determine the effect of oral or intravenous calorie intake on the circulating free fatty acid values. Repeated sampling in 9 patients showed that free fatty acid levels above 1000 mumol/l were seldom found beyond the first 10 hours after admission. Oral calories, chiefly in the form of carbohydrate, reduced free fatty acid by an average of 145 mumol/l for each intake of 90 or more calories (378kF) on the first day. Oral calories (especially carbohydrate) should be considered as possible antilipolytic therapy if it be held desirable to reduce circulating free fatty acid concentrations in patients with acute mycoardial infarction.

摘要

对42例急性心肌梗死患者在发病的头3天进行了研究,以确定口服或静脉摄入热量对循环游离脂肪酸值的影响。对9例患者的重复采样显示,入院后10小时以上很少发现游离脂肪酸水平超过1000μmol/L。口服热量主要以碳水化合物形式存在,在第一天每摄入90千卡或更多热量(378千卡),游离脂肪酸平均降低145μmol/L。如果希望降低急性心肌梗死患者循环游离脂肪酸浓度,口服热量(尤其是碳水化合物)应被视为一种可能的抗脂解疗法。

相似文献

1
Effect of early oral feeding on plasma free fatty acid concentrations in patients in a coronary care unit.早期经口喂养对冠心病监护病房患者血浆游离脂肪酸浓度的影响。
Br Heart J. 1975 Jul;37(7):700-4. doi: 10.1136/hrt.37.7.700.
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[Free fatty acids in the plasma during the early phase following myocardial infarction].
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Br Med J. 1969 Dec 27;4(5686):776-8. doi: 10.1136/bmj.4.5686.776.
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Genetic studies on the arrhythmia in acute myocardial infarction with special reference to serum free fatty acid level.急性心肌梗死心律失常的遗传学研究,特别关注血清游离脂肪酸水平。
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Free fatty acids, heparin, and arrhythmias during experimental myocardial infarction.实验性心肌梗死期间的游离脂肪酸、肝素与心律失常
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引用本文的文献

1
What should he eat, doctor?医生,他该吃些什么?
Br Med J. 1978 Jul 22;2(6132):231-2.

本文引用的文献

1
Microdetermination of long-chain fatty acids in plasma and tissues.血浆和组织中长链脂肪酸的微量测定
J Biol Chem. 1960 Sep;235:2595-9.
2
Some observations on haematocrit changes in patients with acute myocardial infarction.急性心肌梗死患者血细胞比容变化的一些观察
Br Heart J. 1968 May;30(3):344-9. doi: 10.1136/hrt.30.3.344.
3
Intravenous glucose tolerance, insulin, glucose, and free fatty acid levels after myocardial infarction.心肌梗死后的静脉葡萄糖耐量、胰岛素、葡萄糖及游离脂肪酸水平
Br Med J. 1969 Dec 27;4(5686):776-8. doi: 10.1136/bmj.4.5686.776.
4
Albumin quantitation by dye binding and salt fractionation techniques.
Clin Chem. 1972 Jan;18(1):52-6.
5
Metabolic response during impending myocardial infarction. I. Relevance of studies of glucose and fatty acid metabolism in animals.心肌梗死即将发生时的代谢反应。I. 动物体内葡萄糖和脂肪酸代谢研究的相关性。
Circulation. 1972 Feb;45(2):483-90. doi: 10.1161/01.cir.45.2.483.
6
Plasma catecholamines and carbohydrate metabolism in patients with acute myocardial infarction.急性心肌梗死患者的血浆儿茶酚胺与碳水化合物代谢
J Clin Invest. 1974 Aug;54(2):278-86. doi: 10.1172/JCI107763.
7
The effect of a high molar FFA-albumin ratio in the perfusion medium on rhythm and contractility of the isolated rat heart.
J Mol Cell Cardiol. 1973 Jun;5(3):259-73. doi: 10.1016/0022-2828(73)90066-7.
8
A metabolic cause for arrhythmias during acute myocardial hypoxia.
Lancet. 1970 Apr 18;1(7651):813-5. doi: 10.1016/s0140-6736(70)92412-8.
9
Increased plasma-free-fatty-acid concentrations and their significance in patients with acute myocardial infarction.急性心肌梗死患者血浆游离脂肪酸浓度升高及其意义
Lancet. 1969 Dec 6;2(7632):1209-13. doi: 10.1016/s0140-6736(69)90749-1.
10
Relation between serum-free-fatty acids and arrhythmias and death after acute myocardial infarction.急性心肌梗死后血清游离脂肪酸与心律失常及死亡的关系。
Lancet. 1968 Apr 6;1(7545):710-4. doi: 10.1016/s0140-6736(68)92163-6.