Opie L H, Bruyneel K J, Kennelly B M
Br Heart J. 1975 Jul;37(7):700-4. doi: 10.1136/hrt.37.7.700.
Forty-two consecutive patients with acute myocardial infarction were studied over the first 3 days of their illness to determine the effect of oral or intravenous calorie intake on the circulating free fatty acid values. Repeated sampling in 9 patients showed that free fatty acid levels above 1000 mumol/l were seldom found beyond the first 10 hours after admission. Oral calories, chiefly in the form of carbohydrate, reduced free fatty acid by an average of 145 mumol/l for each intake of 90 or more calories (378kF) on the first day. Oral calories (especially carbohydrate) should be considered as possible antilipolytic therapy if it be held desirable to reduce circulating free fatty acid concentrations in patients with acute mycoardial infarction.
对42例急性心肌梗死患者在发病的头3天进行了研究,以确定口服或静脉摄入热量对循环游离脂肪酸值的影响。对9例患者的重复采样显示,入院后10小时以上很少发现游离脂肪酸水平超过1000μmol/L。口服热量主要以碳水化合物形式存在,在第一天每摄入90千卡或更多热量(378千卡),游离脂肪酸平均降低145μmol/L。如果希望降低急性心肌梗死患者循环游离脂肪酸浓度,口服热量(尤其是碳水化合物)应被视为一种可能的抗脂解疗法。