低振幅、极低频磁场治疗膝骨关节炎：一项双盲临床研究

Low-amplitude, extremely low frequency magnetic fields for the treatment of osteoarthritic knees: a double-blind clinical study.

作者信息

Jacobson J I, Gorman R, Yamanashi W S, Saxena B B, Clayton L

机构信息

Institute of Theoretical Physics and Advanced Studies for Biophysical Research, Perspectivism Foundation, 2006 Mainsail Cir, Jupiter, FL 33477-1418, USA.

出版信息

Altern Ther Health Med. 2001 Sep-Oct;7(5):54-64, 66-9.

PMID:11565402

Abstract

CONTEXT

Noninvasive magnetotherapeutic approaches to bone healing have been successful in past clinical studies.

OBJECTIVE

To determine the effectiveness of low-amplitude, extremely low frequency magnetic fields on patients with knee pain due to osteoarthritis.

DESIGN

Placebo-controlled, randomized, double-blind clinical study.

SETTING

4 outpatient clinics.

PARTICIPANTS

176 patients were randomly assigned to 1 of 2 groups, the placebo group (magnet off) or the active group (magnet on).

INTERVENTION

6-minute exposure to each magnetic field signal using 8 exposure sessions for each treatment session, the number of treatment sessions totaling 8 during a 2-week period, yielded patients being exposed to uniform magnetic fields for 48 minutes per treatment session 8 times in 2 weeks. The magnetic fields used in this study were generated by a Jacobson Resonator, which consists of two 18-inch diameter (46-cm diameter) coils connected in series, in turn connected to a function generator via an attenuator to obtain the specific amplitude and frequency. The range of magnetic field amplitudes used was from 2.74 x 10(-7) to 3.4 x 10(-8) G, with corresponding frequencies of 7.7 to 0.976 Hz.

OUTCOME MEASURES

Each subject rated his or her pain level from 1 (minimal) to 10 (maximal) before and after each treatment and 2 weeks after treatment. Subjects also recorded their pain intensity in a diary while outside the treatment environment for 2 weeks after the last treatment session (session 8) twice daily: upon awakening (within 15 minutes) and upon retiring (just before going to bed at night).

RESULTS

Reduction in pain after a treatment session was significantly (P < .001) greater in the magnet-on group (46%) compared to the magnet-off group (8%).

CONCLUSION

Low-amplitude, extremely low frequency magnetic fields are safe and effective for treating patients with chronic knee pain due to osteoarthritis.

摘要

背景

过去的临床研究表明，无创磁疗方法对骨愈合有效。

目的

确定低振幅、极低频磁场对骨关节炎所致膝关节疼痛患者的疗效。

设计

安慰剂对照、随机、双盲临床研究。

地点

4家门诊诊所。

参与者

176名患者被随机分为2组中的1组，即安慰剂组（磁体关闭）或治疗组（磁体开启）。

干预措施

每次治疗时，使用8次暴露疗程，每次暴露于每个磁场信号6分钟，在2周内总共进行8个治疗疗程，这使得患者在2周内每次治疗暴露于均匀磁场48分钟，共8次。本研究中使用的磁场由雅各布森共振器产生，该共振器由两个直径18英寸（46厘米）的线圈串联组成，再通过衰减器连接到函数发生器以获得特定的振幅和频率。使用的磁场振幅范围为2.74×10（-7）至3.4×10（-8）高斯，相应频率为7.7至0.976赫兹。