Spandorfer J
Department of Medicine, Division of Internal Medicine, Jefferson Medical College, Philadelphia, Pennsylvania, USA.
Med Clin North Am. 2001 Sep;85(5):1109-16, v. doi: 10.1016/s0025-7125(05)70366-7.
Patients maintained on warfarin for atrial fibrillation, mechanical heart valves, or deep venous thrombosis may occasionally need to stop their anticoagulation during invasive procedures. This article reviews the literature on bleeding risks of certain procedures, thrombosis risks of stopping anticoagulation, and heparin and warfarin pharmacokinetics. Recommendations regarding how to manage anticoagulated patients are discussed.
因心房颤动、机械心脏瓣膜或深静脉血栓而接受华法林治疗的患者,在进行侵入性操作时偶尔可能需要停用抗凝治疗。本文综述了有关某些操作的出血风险、停用抗凝治疗的血栓形成风险以及肝素和华法林药代动力学的文献。文中还讨论了关于如何管理接受抗凝治疗患者的建议。