Cole Stephanie M, Patterson Matthew B, Cupp Craig L
Department of Otolaryngology, Naval Medical Center San Diego, CA 92134, USA.
Ann Otol Rhinol Laryngol. 2007 Aug;116(8):589-93. doi: 10.1177/000348940711600806.
The objectives of this study were to review perioperative bridging strategies for anticoagulated patients and to describe a novel bridging strategy for tonsillectomy in an anticoagulated patient that addresses both primary and secondary hemorrhage risks.
A literature review and a case report are presented. PubMed was reviewed for evidence-based recommendations on perioperative management of anticoagulated patients. A case report is detailed of a 28-year-old woman with antiphospholipid syndrome on warfarin for high risk of venous thrombosis who underwent tonsillectomy. A perioperative bridging strategy incorporating outpatient low-molecular weight heparin and inpatient unfractionated heparin was implemented to minimize risks of thrombosis and primary and secondary posttonsillectomy hemorrhage.
Limited evidence supports a consensus on the best perioperative management of anticoagulated patients. Tonsillectomy in an anticoagulated patient has not been described previously. The patient in this case underwent successful tonsillectomy with no thrombosis or bleeding after 1 month of follow-up.
Tonsillectomy can be done relatively safely in an anticoagulated patient at high risk for thrombosis. The perioperative bridging strategy should account for its unique risk of primary and secondary postoperative hemorrhage. A proposed algorithm for managing these competing risks is presented.
本研究的目的是回顾抗凝患者的围手术期桥接策略,并描述一种针对抗凝患者扁桃体切除术的新型桥接策略,该策略可解决原发性和继发性出血风险。
本文献综述和病例报告。检索了PubMed以获取关于抗凝患者围手术期管理的循证推荐。详细报告了一名28岁患有抗磷脂综合征且因静脉血栓形成高风险而服用华法林的女性患者接受扁桃体切除术的病例。实施了一种围手术期桥接策略,包括门诊使用低分子量肝素和住院使用普通肝素,以尽量降低血栓形成风险以及扁桃体切除术后原发性和继发性出血风险。
有限的证据支持关于抗凝患者最佳围手术期管理的共识。此前尚未有关于抗凝患者扁桃体切除术的描述。该病例中的患者成功接受了扁桃体切除术,随访1个月后未出现血栓形成或出血情况。
对于血栓形成高风险的抗凝患者,扁桃体切除术可以相对安全地进行。围手术期桥接策略应考虑其术后原发性和继发性出血的独特风险。本文提出了一种管理这些相互竞争风险的算法。