3-磷酸甘油抑制黄色粘球菌的群体运动和聚集。
Glycerol 3-phosphate inhibits swarming and aggregation of Myxococcus xanthus.
作者信息
Moraleda-Muñoz A, Carrero-Lérida J, Extremera A L, Arias J M, Muñoz-Dorado J
机构信息
Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Granada, Spain.
出版信息
J Bacteriol. 2001 Oct;183(20):6135-9. doi: 10.1128/JB.183.20.6135-6139.2001.
Abstract
We have cloned a gene of Myxococcus xanthus with similarities to the permease for glycerol 3-phosphate (G3P) of other bacteria. Expression of the gene increased significantly during the first hours of starvation. Swarming of the wild-type strain was inhibited and aggregation was delayed by G3P. Conversely, a DeltaglpT strain aggregated even on rich medium. These results indicate that G3P may function to regulate the timing of aggregation in M. xanthus.
摘要
我们克隆了一种黄色黏球菌基因，它与其他细菌中甘油3-磷酸（G3P）通透酶具有相似性。在饥饿的最初几个小时内，该基因的表达显著增加。野生型菌株的群体运动受到G3P抑制，聚集也被延迟。相反，ΔglpT菌株即使在丰富培养基上也会聚集。这些结果表明，G3P可能在调节黄色黏球菌聚集的时间方面发挥作用。
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本文引用的文献
1
Cell-to-cell stimulation of movement in nonmotile mutants of Myxococcus.粘球菌非运动突变体中细胞间运动刺激
Proc Natl Acad Sci U S A. 1977 Jul;74(7):2938-42. doi: 10.1073/pnas.74.7.2938.
2
DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.霍乱病原体霍乱弧菌两条染色体的DNA序列。
Nature. 2000 Aug 3;406(6795):477-83. doi: 10.1038/35020000.
3
Pkn9, a Ser/Thr protein kinase involved in the development of Myxococcus xanthus.Pkn9，一种参与黄色黏球菌发育的丝氨酸/苏氨酸蛋白激酶。
Mol Microbiol. 1997 Feb;23(3):459-71. doi: 10.1046/j.1365-2958.1997.d01-1871.x.
4
Recent advances in the social and developmental biology of the myxobacteria.粘细菌社会与发育生物学的最新进展
Microbiol Rev. 1996 Mar;60(1):70-102. doi: 10.1128/mr.60.1.70-102.1996.
5
Reciprocal regulation of the differentiation of Myxococcus xanthus by Pkn5 and Pkn6, eukaryotic-like Ser/Thr protein kinases.类真核丝氨酸/苏氨酸蛋白激酶Pkn5和Pkn6对黄色粘球菌分化的相互调控
Mol Microbiol. 1996 Apr;20(2):435-47. doi: 10.1111/j.1365-2958.1996.tb02630.x.
6
Identification of esg, a genetic locus involved in cell-cell signaling during Myxococcus xanthus development.鉴定esg，一个在黄色粘球菌发育过程中参与细胞间信号传导的基因座。
J Bacteriol. 1993 Dec;175(24):7762-70. doi: 10.1128/jb.175.24.7762-7770.1993.
7
The glpT and glpQ genes of the glycerol regulon in Bacillus subtilis.枯草芽孢杆菌中甘油调节子的glpT和glpQ基因。
Microbiology (Reading). 1994 Apr;140 ( Pt 4):723-30. doi: 10.1099/00221287-140-4-723.
8
Genetic suppression and phenotypic masking of a Myxococcus xanthus frzF- defect.黄色黏球菌frzF缺陷的遗传抑制和表型掩盖
Mol Microbiol. 1995 Feb;15(3):483-94. doi: 10.1111/j.1365-2958.1995.tb02262.x.
9
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Genes Dev. 1995 Apr 15;9(8):972-83. doi: 10.1101/gad.9.8.972.
10
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Mol Microbiol. 1995 Apr;16(2):171-5. doi: 10.1111/j.1365-2958.1995.tb02290.x.
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