Jansen W T, Verheul A F, Veeneman G H, van Boom J H, Snippe H
Eijkman-Winkler Institute for Microbiology, Infectious Diseases, and Inflammation, Vaccines Section, Utrecht University Hospital, 3584 CX, Utrecht, The Netherlands.
Vaccine. 2001 Oct 12;20(1-2):19-21. doi: 10.1016/s0264-410x(01)00263-8.
Recently, the structure for pneumococcal polysaccharide (PS) 17F has been revised. Based on the former PS structure, immunogenicities of PS 17F derived synthetic di-, tri- and tetrasaccharide conjugates have been reported in mice. Here, we present additional data on the immunogenicities of these conjugates in rabbits and re-evaluate the immunogenicity results in the light of the revised PS 17F structure.
