Oddie S, Richmond S, Coulthard M
Neonatal Unit, Royal Victoria Infirmary, Newcastle-upon-Tyne NE1 4LP, UK.
Arch Dis Child. 2001 Oct;85(4):318-20. doi: 10.1136/adc.85.4.318.
As part of a population based regional review of all neonatal readmissions, the incidence of dehydration with hypernatraemia in exclusively breast fed infants was estimated. All readmissions to hospital in the first month of life during 1998 from a population of 32 015 live births were reviewed. Eight of 907 readmissions met the case definition, giving an incidence of at least 2.5 per 10 000 live births. Serum sodium at readmission varied from 150 to 175 mmol/l. One infant had convulsions. The sole explanation for hypernatraemia was unsuccessful breast feeding in all cases. The eight cases are compared with the 65 cases published in the literature since 1979. Presentation, incidence, risk factors, pathophysiology, treatment, and prevention are discussed.
作为对所有新生儿再入院情况进行的基于人群的区域评估的一部分，对纯母乳喂养婴儿中脱水伴高钠血症的发生率进行了估算。对1998年出生的32015名活产婴儿中，出生后第一个月内再次入院的所有情况进行了审查。907例再入院病例中有8例符合病例定义，活产婴儿发生率至少为每10000例中有2.5例。再次入院时血清钠浓度在150至175 mmol/L之间。1名婴儿出现惊厥。所有病例中高钠血症的唯一原因是母乳喂养不成功。将这8例病例与1979年以来文献中发表的65例病例进行了比较。讨论了临床表现、发生率、危险因素、病理生理学、治疗及预防措施。
