Smith J W, Laurence D R, Evans D G
Br Med J. 1975 Aug 23;3(5981):453-5. doi: 10.1136/bmj.3.5981.453.
Recommendations for the prevention of tetanus in the wounded have been revised to incorporate the use of human tetanus immunoglobulin, which is now available in the United Kingdom. Surgical toilet is of prime importance for all wounds, and is usually sufficient for tetanus prophylaxis in patients with wounds that are less than six hours old, clean, non-penetrating, and with negligible tissue damage. Human tetanus immunoglobulin should be given to patients with more serious wounds sho have had toxoid injections over 10 years earlier, had an incomplete course, or do not know their immunity status. The importance of active immunization is emphasized. The recommendations should be regarded as guidelines as the circumstances in individual cases will differ.
预防伤员破伤风的建议已修订，纳入了人破伤风免疫球蛋白的使用，目前英国已有该产品。外科清创对所有伤口至关重要，对于伤口小于6小时、清洁、非穿透性且组织损伤可忽略不计的患者，通常足以预防破伤风。对于伤口较严重、10多年前曾接种过类毒素、接种疗程不完整或不知道自身免疫状况的患者，应给予人破伤风免疫球蛋白。强调了主动免疫的重要性。由于个别情况会有所不同，这些建议应被视为指导方针。
