Hoffman R A, Li C L
Department of Otolaryngology/Head and Neck Surgery, Beth Israel Medical Center, New York, NY 10003, USA.
Laryngoscope. 2001 Sep;111(9):1636-8. doi: 10.1097/00005537-200109000-00027.
OBJECTIVES/HYPOTHESIS: To study the efficacy and safety of topical tetracaine anesthesia for office myringotomy and myringotomy with a tube.
Retrospective review of patients undergoing office myringotomy, with or without tube insertion, performed over a 4-year period.
A topical solution of 8% tetracaine base in 70% isopropyl alcohol was used in 381 ears. Five to 10 drops of the solution were applied to the tympanic membrane for 10 to 15 minutes and aspirated. Myringotomy was performed either with a myringotomy knife or with a CO(2) laser (OtoLAM).
Topical tetracaine was used in all 231 ears (100%) undergoing myringotomy without a tube and 150 of 212 ears (71%) undergoing myringotomy with a tube. Tetracaine alone was effective in providing tympanic membrane anesthesia in 95% of myringotomy without a tube (220 ears) and in 93% of myringotomy with a tube (139 ears). There were six complications, including five cases of severe vertigo and one unusual prolonged, transient facial nerve weakness.
Topical tetracaine is efficacious and safe for use in office myringotomy.
目的/假设：研究丁卡因局部麻醉用于门诊鼓膜切开术及鼓膜切开置管术的有效性和安全性。
回顾性分析4年间接受门诊鼓膜切开术（无论是否置管）的患者。
381耳使用8%丁卡因碱溶于70%异丙醇的局部溶液。将5至10滴该溶液滴于鼓膜上10至15分钟后吸出。使用鼓膜切开刀或二氧化碳激光（OtoLAM）进行鼓膜切开术。
所有231耳（100%）鼓膜切开未置管及212耳中的150耳（71%）鼓膜切开置管均使用了丁卡因局部麻醉。仅丁卡因就在95%的鼓膜切开未置管（220耳）及93%的鼓膜切开置管（139耳）中有效提供了鼓膜麻醉。有6例并发症，包括5例严重眩晕和1例罕见的长时间、短暂性面神经麻痹。
丁卡因局部麻醉用于门诊鼓膜切开术有效且安全。
