用氩激光或微型刀进行鼓膜切开术后鼓膜愈合情况：大鼠实验研究
Tympanic membrane healing in myringotomies performed with argon laser or microknife: an experimental study in rats.
作者信息
Castagno Lucio Almeida, Lavinksy Luiz
机构信息
Departamento de Oftalmologia e Otorrinolaringologia, Universidade Federal do Rio Grande do Sul, RS.
出版信息
Braz J Otorhinolaryngol. 2006 Nov-Dec;72(6):794-9. doi: 10.1016/s1808-8694(15)31046-6.
UNLABELLED
Secretory otitis media (SOM) and recurrent acute otitis media (RAOM) may require surgical treatment to proper ventilate the middle ear. Incisional myringotomy is usually done under microscopy with a micro-knife, but it remains patent for just a few days. Recent research indicates that laser assisted myringotomies remain open much longer, allowing middle ear ventilation and healing.
MATERIAL AND METHODS
In this experimental study 34 white, male, adult, Wistar rats, without middle ear disease were submitted to anesthesia with ketamine 27 mg/kg and xylazine 2,7 mg/kg. Incisional myringotomy was done on the right ear, while laser myringotomy was done on the left. Myringotomies were evaluated periodically until healing.
RESULTS
The healing times were equivalent. All myringotomies healed within 10 days.
CONCLUSION
Argon laser assisted myringotomy healed just as early on as incisional myringotomy on Wistar rats without middle ear diseases.
未标注
分泌性中耳炎（SOM）和复发性急性中耳炎（RAOM）可能需要手术治疗以实现中耳的适当通气。切开鼓膜造孔术通常在显微镜下用微型刀进行，但仅能保持通畅几天。最近的研究表明，激光辅助鼓膜造孔术保持开放的时间要长得多，可实现中耳通气和愈合。
材料与方法
在本实验研究中，34只无中耳疾病的成年雄性白色Wistar大鼠用27mg/kg氯胺酮和2.7mg/kg甲苯噻嗪麻醉。右耳进行切开鼓膜造孔术，左耳进行激光鼓膜造孔术。定期评估鼓膜造孔术直至愈合。
结果
愈合时间相当。所有鼓膜造孔术均在10天内愈合。
结论
在无中耳疾病的Wistar大鼠中，氩激光辅助鼓膜造孔术与切开鼓膜造孔术愈合同样早。
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