Phosphorylation of mammalian eIF4E by Mnk1 and Mnk2: tantalizing prospects for a role in translation.

作者信息

Mahalingam M, Cooper J A

机构信息

Fred Hutchinson Cancer Research Center, P.O. Box 19024, 1100 Fairview Avenue North, A2-025, Seattle, Washington 98109-1024, USA.

出版信息

Prog Mol Subcell Biol. 2001;27:132-42.

PMID:11575158

Abstract

摘要

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Phosphorylation of mammalian eIF4E by Mnk1 and Mnk2: tantalizing prospects for a role in translation.

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Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.人类真核生物翻译起始因子4G（eIF4G）募集丝裂原活化蛋白激酶相互作用激酶1（mnk1）以磷酸化真核生物翻译起始因子4E（eIF4E）。

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