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审核能否改善普通牙科诊所的抗生素处方情况?

Can audit improve antibiotic prescribing in general dental practice?

作者信息

Palmer N A, Dailey Y M, Martin M V

机构信息

Department of Clinical Dental Sciences, University of Liverpool.

出版信息

Br Dent J. 2001 Sep 8;191(5):253-5. doi: 10.1038/sj.bdj.4801156a.

Abstract

OBJECTIVE

To investigate whether clinical audit can improve general dental practitioners' prescribing of antibiotics.

DESIGN

An intervention study carried out in general dental practice in the North West of England.

METHOD

Information was collected over an initial six-week period from 175 general dental practitioners on their current antibiotic prescribing practices. The information collected was the antibiotic prescribed including dose, frequency and duration, the clinically presenting signs and conditions, the medical history (if for prophylaxis), and any other reasons for prescribing. This was compared to the practitioners' antibiotic prescribing for a further six-week period following an audit, which included an educational component and the issuing of guidelines.

RESULTS

During the initial period practitioners issued 2316 prescriptions for antibiotics. This was reduced by 42.5% to 1330 during the audit. The majority of the antibiotics (81%) for both periods were prescribed for therapeutic reasons. The most commonly prescribed antibiotics were amoxycillin (57.6%), metronidazole (23.8%), penicillin (9.3%), erythromycin (4.8%) and a combination of amoxycillin and metronidazole (1.7%). The antibiotic regimens used by practitioners were significantly changed by the audit (P<0.001) and there was a significant reduction in the number of prescriptions (P<0.05) which did not conform to national guidelines.

CONCLUSIONS

The results from this investigation support the conclusion that clinical audit, with the issuing of guidelines and an educational component, can change prescribing practices leading to a more rational and appropriate use of antibiotics in general dental practice.

摘要

目的

调查临床审计是否能改善普通牙科医生对抗生素的处方开具情况。

设计

在英格兰西北部的普通牙科诊所开展的一项干预性研究。

方法

在最初的六周内收集了175名普通牙科医生当前抗生素处方开具情况的信息。收集的信息包括所开具的抗生素(包括剂量、频率和疗程)、临床症状和病情、病史(如果是用于预防)以及任何其他处方开具原因。将这些信息与医生在接受包括教育内容和指南发放的审计后的接下来六周内的抗生素处方开具情况进行比较。

结果

在初始阶段,医生开具了2316份抗生素处方。在审计期间,这一数量减少了42.5%,降至1330份。两个阶段中,大多数抗生素(81%)是出于治疗目的而开具的。最常开具的抗生素是阿莫西林(57.6%)、甲硝唑(23.8%)、青霉素(9.3%)、红霉素(4.8%)以及阿莫西林和甲硝唑的联合用药(1.7%)。审计显著改变了医生使用的抗生素治疗方案(P<0.001),并且不符合国家指南的处方数量显著减少(P<0.05)。

结论

本次调查结果支持以下结论,即临床审计结合指南发放和教育内容,可以改变处方开具行为,从而在普通牙科实践中更合理、恰当地使用抗生素。

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