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临床审计对普通牙科实践中抗生素处方的影响。

The impact of clinical audit on antibiotic prescribing in general dental practice.

作者信息

Chate R A C, White S, Hale L R O, Howat A P, Bottomley J, Barnet-Lamb J, Lindsay J, Davies T I, Heath J M

机构信息

Orthodontic Department, Essex County Hospital, Lexden Road, Colchester C03 3NB.

出版信息

Br Dent J. 2006 Nov 25;201(10):635-41. doi: 10.1038/sj.bdj.4814261.

Abstract

OBJECTIVE

To reduce the number of antibiotics inappropriately prescribed by general dental practitioners, and to increase overall prescription accuracy.

DESIGN

A prospective clinical audit carried out between September and March of 2002-3 and 2003-4.

SETTING

General dental practices in Eastern England.

SUBJECTS AND METHODS

The pre-audit antibiotic prescribing practices of 212 general dental practitioners were recorded over an initial six week period. On each occasion this included which antibiotic had been chosen, together with its dose, frequency and duration, as well as the clinical condition and reason for which the prescription had been raised. When related to prophylaxis, the patient's medical history was also noted. Following education on contemporary prescribing guidelines, presentations which illustrated the practitioners' previous errors, and the agreement of standards to be achieved, the process was repeated for another six weeks, and the results compared.

RESULTS

In the pre-audit period, 2,951 antibiotic prescriptions were issued, and during the audit this was reduced by 43.6% to 1,665. The majority were for therapeutic reasons, with only 10.5% and 13.6% for medical prophylaxis during the pre-audit and audit periods respectively. Over both periods, amoxicillin and metronidazole were the two most commonly prescribed antimicrobials (63.4% and 21.2% respectively). In the pre-audit period, only 43% of all prescriptions were error free in dose, frequency, and/or duration of use, but this rose significantly to 78% during the audit. Equally, using contemporary published guidelines, out of all the prescriptions made in the pre-audit period, only 29.2% were deemed to be justified, as compared to 48.5% during the audit.

CONCLUSIONS

Clinical audit, in conjunction with education, and prescribing guidelines can favourably change antibiotic prescribing patterns among general dental practitioners.

摘要

目的

减少普通牙科医生不合理开具抗生素的数量,并提高总体处方准确性。

设计

在2002 - 2003年9月至3月以及2003 - 2004年进行的一项前瞻性临床审计。

地点

英格兰东部的普通牙科诊所。

对象与方法

在最初的六周期间记录了212名普通牙科医生的审计前抗生素处方习惯。每次记录包括所选的抗生素及其剂量、频率和疗程,以及开具处方的临床情况和原因。与预防性用药相关时,还记录了患者的病史。在接受关于当代处方指南的教育、展示其先前错误的演示文稿以及达成要实现的标准后,该过程再重复六周,并比较结果。

结果

在审计前阶段,共开具了2951份抗生素处方,审计期间减少了43.6%,降至1665份。大多数是出于治疗原因,在审计前和审计期间,用于医疗预防的分别仅占10.5%和13.6%。在这两个阶段,阿莫西林和甲硝唑是最常开具处方的两种抗菌药物(分别为63.4%和21.2%)。在审计前阶段,所有处方中只有43%在剂量、频率和/或使用疗程方面没有错误,但在审计期间这一比例显著上升至78%。同样,根据当代已发表的指南,在审计前阶段开具的所有处方中,只有29.2%被认为是合理的,而在审计期间这一比例为48.5%。

结论

临床审计与教育以及处方指南相结合,可以有利地改变普通牙科医生的抗生素处方模式。

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