Chida M, Handa M, Yaginuma G, Suda H, Maeda S, Kazuma H
Department of Surgery, Sendai Kosei Hospital, Sendai, Japan.
Jpn J Thorac Cardiovasc Surg. 2001 Sep;49(9):576-80. doi: 10.1007/BF02913535.
Three men age: 39-51 years (mean: 43.3 years) with T4N0 lung cancer infiltrating the distal aortic arch underwent combined resection of the left upper lobe, distal aortic arch, and left subclavian artery using partial extracorponeal circulation. Selective cerebral perfusion was used in 2. One underwent induction therapy (CDDP + VP - 16 x 2 + radiation 30 Gy), and all underwent adjuvant therapy. No postoperative complications or postoperative death occurred. Average ICU stay was 2.3 days. All patients are alive without local recurrence. Two were disease-free 37 and 26 months after surgery, and 1 had adrenal gland metastasis 8 months after surgery. Extended resection of the aortic arch in lung cancer is thus feasible and worthwhile in patients with T4N0 non-small-cell lung cancer.
三名年龄在39至51岁（平均43.3岁）的T4N0期肺癌侵犯远端主动脉弓的患者，采用部分体外循环技术接受了左上叶、远端主动脉弓和左锁骨下动脉的联合切除术。其中2例采用了选择性脑灌注。1例接受了诱导治疗（顺铂+依托泊苷×2+放疗30 Gy），所有患者均接受了辅助治疗。术后未发生并发症或死亡。平均重症监护病房停留时间为2.3天。所有患者均存活，无局部复发。2例术后37个月和26个月无疾病复发，1例术后8个月出现肾上腺转移。因此，对于T4N0期非小细胞肺癌患者，肺癌主动脉弓扩大切除术是可行且值得的。
