儿童期首次住院时的情感症状与成年期的抑郁症状：一项“追赶”研究。
Affective symptoms at index hospitalization in childhood and depressive symptoms in adulthood: a "catch-up" study.
作者信息
Brieger P, Blöink R, Sommer S, Marneros A
机构信息
Division of Social Psychiatry, University Hospital for Psychiatry and Psychotherapy, Martin-Luther-University Halle-Wittenberg, 06097 Halle/Saale, Germany.
出版信息
J Affect Disord. 2001 Oct;66(2-3):263-6. doi: 10.1016/s0165-0327(00)00302-5.
PURPOSE
To analyze whether affective symptoms during psychiatric treatment in childhood or adolescence could predict the later development of depressive symptoms.
METHOD
We used a "catch-up" design. A cohort of former child and adolescent psychiatric patients was assessed in adulthood with standardized instruments according to the criteria of ICD-10 (SCAN) and dimensional values for depression (both self-reported and observer-rated). Initial affective symptoms had been extracted from clinical records according to a standardized system (AMDP).
RESULTS
We assessed 164 former patients. Twelve percent of these fulfilled diagnostic criteria of an affective disorder (F3) according to ICD-10. In univariate analyses of variance the depression scores were significantly related to affective symptoms during childhood treatment, even if the presence of an affective disorder at catch-up was considered as an independent covariate variable. Nevertheless, the latter variable explained a large part of the variance of depression scores, while initial affective symptoms explained no more than 6%.
CONCLUSION
Affective symptoms in childhood and adolescence may predict the later development of subthreshold depressive symptomatology.
目的
分析儿童期或青少年期精神治疗期间的情感症状是否能预测抑郁症状的后期发展。
方法
我们采用了“追踪”设计。一组 former 儿童和青少年精神科患者在成年期根据 ICD - 10（SCAN）标准和抑郁的维度值（自我报告和观察者评定）使用标准化工具进行评估。初始情感症状已根据标准化系统（AMDP）从临床记录中提取。
结果
我们评估了164名 former 患者。其中12%根据 ICD - 10 符合情感障碍（F3）的诊断标准。在单因素方差分析中，抑郁评分与儿童期治疗期间的情感症状显著相关，即使将追踪时情感障碍的存在视为一个独立的协变量。然而，后一个变量解释了抑郁评分方差的很大一部分，而初始情感症状解释的不超过6%。
结论
儿童期和青少年期的情感症状可能预测阈下抑郁症状的后期发展。
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