Ho E, Collantes A, Kapur B M, Moretti M, Koren G
Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ont., Canada.
Biol Neonate. 2001;80(3):219-22. doi: 10.1159/000047146.
To create a nomogram that will guide lactating women who drink socially on how to avoid neonatal exposure to ethanol through breast milk.
Pharmacokinetic modeling of ethanol elimination from milk based on reference values. Calculation of the time to zero alcohol in breast milk for a range of doses and body weights.
The elimination of alcohol and time-to-zero levels in breast milk are described in a nomogram as a function of the amount of alcohol consumed and the body weight of the woman.
Careful planning of a breast feeding schedule, by storing milk before drinking and/or waiting for complete alcohol elimination from the breast milk, can ensure women that their babies are not exposed to any alcohol.
创建一种列线图,以指导有社交性饮酒行为的哺乳期妇女如何避免新生儿通过母乳接触乙醇。
基于参考值对母乳中乙醇消除进行药代动力学建模。计算一系列剂量和体重情况下母乳中酒精归零的时间。
列线图将母乳中酒精消除情况和酒精归零时间描述为饮酒量和女性体重的函数。
通过在饮酒前储存母乳和/或等待母乳中酒精完全消除,精心规划母乳喂养时间表,可确保女性的婴儿不接触任何酒精。