Teive H A, Zavala J A, Iwamoto F M, Sá D, Carraro H, Werneck L C
Setor de Distúrbios do Movimento, Serviço de Neurologia, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brasil.
Arq Neuropsiquiatr. 2001 Sep;59(3-A):633-6.
Charcot described many neurological diseases in the 19th century, particularly in movement disorders. Charcot contributed in the clinical description of Parkinson's disease, and introduced its first pharmacological treatment. He also studied the hyperkinesias, e.g. of Tourette syndrome, differential diagnosis of tremors, dystonias, choreas and startle disease. Marsden, who died recently, was an exponent in the study of Movement Disorders, with many publications in this field in the 20th century. His most important contributions are definitions and classifications of movement disorders, such as Parkinson's disease, dystonia, myoclonus, essential tremor, the description of the syndromes "Painful Legs Moving Toes", "Gait Ignition Failure" and "Primary Writing Tremor". The contributions of Charcot in the 19th century and Marsden in the 20th century to the movement disorders allow us to conclude that both of them were the most representative icons in this field in the past two centuries.
夏科在19世纪描述了许多神经系统疾病，尤其是在运动障碍方面。夏科对帕金森病的临床描述做出了贡献，并引入了其首个药物治疗方法。他还研究了运动亢进，如抽动秽语综合征、震颤的鉴别诊断、肌张力障碍、舞蹈症和惊吓症。最近去世的马斯登是运动障碍研究领域的一位杰出人物，在20世纪该领域发表了许多著作。他最重要的贡献是对运动障碍的定义和分类，如帕金森病、肌张力障碍、肌阵挛、特发性震颤，以及对“腿痛-足动综合征”“步态启动失败”和“原发性书写震颤”等综合征的描述。夏科在19世纪和马斯登在20世纪对运动障碍的贡献使我们可以得出结论，他们两人都是过去两个世纪该领域最具代表性的人物。
